Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane.
about
Structure-function relationships of ErbB RTKs in the plasma membrane of living cellsSubcellular Partitioning of Protein Tyrosine Phosphatase 1B to the Endoplasmic Reticulum and Mitochondria Depends Sensitively on the Composition of Its Tail AnchorSingle Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated PitsAberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src.The potential of optical proteomic technologies to individualize prognosis and guide rational treatment for cancer patientsA KCNC3 mutation causes a neurodevelopmental, non-progressive SCA13 subtype associated with dominant negative effects and aberrant EGFR trafficking.Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice.Neurotensin (NTS) and its receptor (NTSR1) causes EGFR, HER2 and HER3 over-expression and their autocrine/paracrine activation in lung tumors, confirming responsiveness to erlotinib.Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants.Endocytosis and intracellular trafficking of ErbBs.The signaling and transformation potency of the overexpressed HER2 protein is dependent on the normally-expressed EGFR.Quantitation of the effect of ErbB2 on epidermal growth factor receptor binding and dimerizationIdentification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer.Cigarette Smoke Induces Human Epidermal Receptor 2-Dependent Changes in Epithelial Permeability.Systems biological analysis of epidermal growth factor receptor internalization dynamics for altered receptor levels.HER2-positive male breast cancer: an update.Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases.The challenges of integrating molecular imaging into the optimization of cancer therapy.Physiological mechanisms of signal termination in biological systems.EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling.Dual specificity phosphatases 10 and 16 are positive regulators of EGF-stimulated ERK activity: indirect regulation of ERK signals by JNK/p38 selective MAPK phosphatases.Diminished functional role and altered localization of SHP2 in non-small cell lung cancer cells with EGFR-activating mutations.A novel cross-talk between endothelin and ErbB receptors controlling glutamate transporter expression in astrocytes.Phosphosite-Specific Antibodies: A Brief Update on Generation and Applications.Increased EHD1 in non-small cell lung cancer predicts poor survival.Dynamic conformational transitions of the EGF receptor in living mammalian cells determined by FRET and fluorescence lifetime imaging microscopy.
P2860
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P2860
Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane.
@en
Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane.
@nl
type
label
Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane.
@en
Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane.
@nl
prefLabel
Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane.
@en
Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane.
@nl
P2860
P1433
P1476
Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane.
@en
P2093
Martin Offterdinger
Philippe I Bastiaens
P2860
P304
P356
10.1111/J.1600-0854.2007.00665.X
P577
2007-11-13T00:00:00Z