about
Mediation of organismal aging and somatic proteostasis by the germlineThe ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan.The Mechanistic Links Between Proteasome Activity, Aging and Age-related Diseases.Proteostasis and aging of stem cells.The role of protein clearance mechanisms in organismal ageing and age-related diseases.Embryonic stem cells: a novel paradigm to study proteostasis?Regulation of glycogen synthesis by the laforin-malin complex is modulated by the AMP-activated protein kinase pathway.Carboxyl-terminal fragment of amyloid precursor protein and hydrogen peroxide induce neuronal cell death through different pathways.Neurotoxic effects of trimethyltin and triethyltin on human fetal neuron and astrocyte cultures: a comparative study with rat neuronal cultures and human cell lines.Proteostasis of Huntingtin in Health and DiseaseFOXO4 is necessary for neural differentiation of human embryonic stem cells.Down's syndrome astrocytes have greater antioxidant capacity than euploid astrocytes.Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy.RPN-6 determines C. elegans longevity under proteotoxic stress conditions.A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells.Mechanisms of protein homeostasis (proteostasis) maintain stem cell identity in mammalian pluripotent stem cells.Insights into the ubiquitin-proteasome system of human embryonic stem cells.Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.Author Correction: Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patientsInduced pluripotent stem cells from Huntington's disease patients: a promising approach to define and correct disease-related alterationsAuthor Correction: The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patientsThe autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagyThe E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cellsProstaglandin signals from adult germ stem cells delay somatic aging of Caenorhabditis elegansMechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutationsAuthor Correction: Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophyThe ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
David Vilchez
@ast
David Vilchez
@en
David Vilchez
@es
David Vilchez
@nl
David Vilchez
@sl
type
label
David Vilchez
@ast
David Vilchez
@en
David Vilchez
@es
David Vilchez
@nl
David Vilchez
@sl
prefLabel
David Vilchez
@ast
David Vilchez
@en
David Vilchez
@es
David Vilchez
@nl
David Vilchez
@sl
P1053
A-8446-2008
P106
P21
P31
P3829
P496
0000-0002-0801-0743