Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.
about
Role of NADPH oxidase in formation and function of multinucleated giant cellsModulation of osteoclast differentiation and bone resorption by Rho GTPasesOxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasisRole of CrkII Signaling in RANKL-Induced Osteoclast Differentiation and Function.Phospholipase C gamma 2 is critical for development of a murine model of inflammatory arthritis by affecting actin dynamics in dendritic cells.MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling3-Hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin)-induced 28-kDa interleukin-1β interferes with mature IL-1β signalingPathways that Regulate ROS Scavenging Enzymes, and Their Role in Defense Against Tissue Destruction in Periodontitis.Down-regulation of Irf8 by Lyz2-cre/loxP accelerates osteoclast differentiation in vitro.Regulation of Embryonic and Postnatal Development by the CSF-1 Receptor.siRNA knock-down of RANK signaling to control osteoclast-mediated bone resorption.Osteoclast motility: putting the brakes on bone resorption.TRP14 inhibits osteoclast differentiation via its catalytic activitySelective targeting of RANK signaling pathways as new therapeutic strategies for osteoporosis.The actin binding protein adseverin regulates osteoclastogenesisPodosome organization drives osteoclast-mediated bone resorption.Small interfering RNA knocks down the molecular target of alendronate, farnesyl pyrophosphate synthase, in osteoclast and osteoblast cultures.Stimulation of osteoclast formation by RANKL requires interferon regulatory factor-4 and is inhibited by simvastatin in a mouse model of bone loss.Osteoclasts lacking Rac2 have defective chemotaxis and resorptive activity.Rac deletion in osteoclasts causes severe osteopetrosisRNA therapeutics targeting osteoclast-mediated excessive bone resorption.Systems biology approach to studying proliferation-dependent prognostic subnetworks in breast cancer.The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts.The collection of NFATc1-dependent transcripts in the osteoclast includes numerous genes non-essential to physiologic bone resorption.Neutrophil transcriptional profile changes during transit from bone marrow to sites of inflammationOdontoclastogenesis of mouse papilla-derived MDPC-23 cells induced by lipopolysaccharide.Biphosphonates-associated osteonecrosis of the jaw: the role of gene-environment interaction.Molecular regulatory mechanisms of osteoclastogenesis through cytoprotective enzymes.Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo.The anabolic response to parathyroid hormone is augmented in Rac2 knockout mice.The Keap1/Nrf2 protein axis plays a role in osteoclast differentiation by regulating intracellular reactive oxygen species signaling.Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosisA distinctive role of the leukotriene B4 receptor BLT1 in osteoclastic activity during bone loss.Wnt and Rho GTPase signaling in osteoarthritis development and intervention: implications for diagnosis and therapy.Signal transduction pathways in chronic inflammatory autoimmune disease: small GTPases.Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases.Phosphoglycerol dihydroceramide, a distinctive ceramide produced by Porphyromonas gingivalis, promotes RANKL-induced osteoclastogenesis by acting on non-muscle myosin II-A (Myh9), an osteoclast cell fusion regulatory factor.Regulation of bone mass and osteoclast function depend on the F-actin modulator SWAP-70.A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritisIKKbeta activation is sufficient for RANK-independent osteoclast differentiation and osteolysis.
P2860
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P2860
Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.
@en
Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.
@nl
type
label
Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.
@en
Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.
@nl
prefLabel
Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.
@en
Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.
@nl
P2093
P356
P1476
Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.
@en
P2093
Chunxiang Sun
Dina Lebowitz
Herman Thang
Marc D Grynpas
Yongqiang Wang
P304
P356
10.1359/JBMR.071013
P577
2008-02-01T00:00:00Z