Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.
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Attention to Background Strain Is Essential for Metabolic Research: C57BL/6 and the International Knockout Mouse ConsortiumReview and Hypothesis. New insights into the reaction mechanism of transhydrogenase: Swivelling the dIII component may gate the proton channelGLUT4 defects in adipose tissue are early signs of metabolic alterations in Alms1GT/GT, a mouse model for obesity and insulin resistanceSimilarity in Transcytosis of nNOSα in Enteric Nerve Terminals and Beta Cells of Pancreatic IsletAnalysis of gene expression in pancreatic islets from diet-induced obese mice.Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function.The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways.Regulation of insulin secretion: role of mitochondrial signalling.Diet-induced obesity in two C57BL/6 substrains with intact or mutant nicotinamide nucleotide transhydrogenase (Nnt) geneGlobal genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolismDefective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice.Simultaneous measurement of insulin sensitivity, insulin secretion, and the disposition index in conscious unhandled miceDifferential Insulin Secretion of High-Fat Diet-Fed C57BL/6NN and C57BL/6NJ Mice: Implications of Mixed Genetic Background in Metabolic Studies.Metabolic effects of intermittent hypoxia in mice: steady versus high-frequency applied hypoxia daily during the rest period.Vitamin E and vitamin C do not reduce insulin sensitivity but inhibit mitochondrial protein expression in exercising obese rats.Glucose metabolism in vivo in four commonly used inbred mouse strains.Should diabetic women with breast cancer have their own intervention studies?Pancreatic islet expression profiling in diabetes-prone C57BLKS/J mice reveals transcriptional differences contributed by DBA loci, including Plagl1 and NntMitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload.Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.Mammalian NADH:ubiquinone oxidoreductase (Complex I) and nicotinamide nucleotide transhydrogenase (Nnt) together regulate the mitochondrial production of H₂O₂--implications for their role in disease, especially cancer.The Pancreatic β-Cell: A Bioenergetic Perspective.High fat feeding unmasks variable insulin responses in male C57BL/6 mouse substrains.A Chromosome 13 locus is associated with male-specific mortality in mice.Cleavage Speed and Blastomere Number in DBA/2J Compared with C57BL/6J Mouse Embryos.Deletion of Protein Kinase D1 in Pancreatic Beta Cells Impairs Insulin Secretion in High-Fat Fed Mice.Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity.Considerations and guidelines for mouse metabolic phenotyping in diabetes research.A novel mechanism regulating insulin secretion involving Herpud1 in mice.A Mouse Model of Beta-Cell Dysfunction as Seen in Human Type 2 Diabetes.
P2860
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P2860
Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.
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2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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name
Increased nicotinamide nucleot ...... train susceptible to diabetes.
@en
Increased nicotinamide nucleot ...... train susceptible to diabetes.
@nl
type
label
Increased nicotinamide nucleot ...... train susceptible to diabetes.
@en
Increased nicotinamide nucleot ...... train susceptible to diabetes.
@nl
prefLabel
Increased nicotinamide nucleot ...... train susceptible to diabetes.
@en
Increased nicotinamide nucleot ...... train susceptible to diabetes.
@nl
P2093
P50
P1433
P1476
Increased nicotinamide nucleot ...... strain susceptible to diabetes
@en
P2093
J Favaloro
J Proietto
S Andrikopoulos
P2860
P2888
P304
P356
10.1007/S00125-007-0814-X
P577
2007-10-06T00:00:00Z