Stabilization of hyperdynamic microtubules is neuroprotective in amyotrophic lateral sclerosis. - Wikidata - wikimedia - TriplyDB

Stabilization of hyperdynamic microtubules is neuroprotective in amyotrophic lateral sclerosis.

Stabilization of hyperdynamic microtubules is neuroprotective in amyotrophic lateral sclerosis.

http://www.wikidata.org/entity/Q46977479

about

Dysregulated axonal RNA translation in amyotrophic lateral sclerosis Neurodegeneration and microtubule dynamics: death by a thousand cuts Microtubule-stabilizing agents as potential therapeutics for neurodegenerative disease Tau Biology and Tau-Directed Therapies for Alzheimer's Disease A Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During Disease ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease Deficits in axonal transport precede ALS symptoms in vivo.An assay to image neuronal microtubule dynamics in mice Measurement of protein synthesis using heavy water labeling and peptide mass spectrometry: Discrimination between major histocompatibility complex allotypes.Progress in therapy development for amyotrophic lateral sclerosis Cerebrospinal fluid-based kinetic biomarkers of axonal transport in monitoring neurodegeneration.Mining the secrets of the CSF: developing biomarkers of neurodegeneration.Opening Pandora's jar: a primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders.Stathmin 1/2-triggered microtubule loss mediates Golgi fragmentation in mutant SOD1 motor neurons.Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination.Back to the tubule: microtubule dynamics in Parkinson's disease.Microtubule-Targeting Agents Enter the Central Nervous System (CNS): Double-edged Swords for Treating CNS Injury and Disease.Transcriptional analysis reveals distinct subtypes in amyotrophic lateral sclerosis: implications for personalized therapy.FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination.Stability properties of neuronal microtubules.Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugs.Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?Aberrant molecular properties shared by familial Parkinson's disease-associated mutant UCH-L1 and carbonyl-modified UCH-L1.Microtubules in health and degenerative disease of the nervous system.Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation.Profilin Directly Promotes Microtubule Growth through Residues Mutated in Amyotrophic Lateral Sclerosis.MGRN1-mediated ubiquitination of α-tubulin regulates microtubule dynamics and intracellular transport.Microtubule destruction induces tau liberation and its subsequent phosphorylation.Microtubule Dynamicity Is More Important than Stability in Memory Formation: an In Vivo Study.Association of Microtubule Dynamics with Chronic Epilepsy.

P2860

Q26753110-347164A4-DF8B-46DB-9B76-E3C49B7C2DC9 Q26781649-618C2A45-9839-4D03-84BE-AA8543626009 Q26865234-7C979384-C080-46BC-9178-8187CA1D85E5 Q28071398-1C7E1728-A46C-4D16-960C-9E0109E1559D Q28079299-5A85FEF1-7857-4E05-84C7-7569A2A4421F Q28392297-3E977892-ED0E-494D-9DFB-20A35F0A8B0E Q30497554-1F6AF7E5-EC38-428A-9663-6972E0FB4417 Q30587931-B7CFA633-024B-4013-BBB1-5D79338ADB3E Q33959195-22A77DDC-917A-48B0-AD8E-678A7F681333 Q34640800-09DFE073-F793-4976-88FB-5A7088DDA8DD Q36190765-1FB59E86-F50F-4694-B484-2192B30F1844 Q36190786-705D4972-98CE-48D2-850E-7FC8F7D5F7EE Q36517220-3C101A50-6810-4814-9890-01FC73D16856 Q36986580-432974EC-B4E1-49F7-BF7D-5C775325BFCC Q37014395-58F58339-6E9F-4212-8CB6-EB5500FCA7F4 Q37463947-5B359F73-E1DC-475D-AC83-EB2A0E72B775 Q37590635-12CBB006-6667-4F18-836A-233ACC028395 Q38307155-59299903-B571-4154-B9AA-53565FA358E6 Q38542939-F89D78B6-0369-4A09-8CD9-9984814EA33D Q38712151-29AFCE28-B449-49F7-98E9-4E68C8F45987 Q38737712-E5C0BB19-1F9A-496C-8482-1869B1C43F70 Q39052949-5C5DEDDB-3AC1-4A78-88CC-B5C5EE5CF1C1 Q39149919-8530A3B2-AD51-4374-AC94-2D3B7552DB68 Q40016575-7F7880FF-22F6-4652-9B1F-92C534906D69 Q41576648-2A936C6A-D112-4195-AAF1-7276C26EFA57 Q41786636-16AD895A-8572-40B9-A486-8ADCE85AC057 Q47412043-25AE3D57-707F-466D-827B-60659C3E4F37 Q48115125-D55FAD6A-7283-4B17-BDF7-6A62F51B4E06 Q48159838-53168422-C869-44DD-B96C-1E2F70329649 Q48297603-47CA4060-3389-436A-B2F2-699037BE5740 Q52149164-AEB62B83-0FD2-42A7-BEF5-EF73E4E8E02C

P2860

Stabilization of hyperdynamic microtubules is neuroprotective in amyotrophic lateral sclerosis.

http://www.wikidata.org/entity/Q46977479

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年学术文章

@wuu

2007年学术文章

@zh

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

@zh-hant

name

Stabilization of hyperdynamic ...... amyotrophic lateral sclerosis.

@en

Stabilization of hyperdynamic ...... amyotrophic lateral sclerosis.

@nl

type

label

Stabilization of hyperdynamic ...... amyotrophic lateral sclerosis.

@en

Stabilization of hyperdynamic ...... amyotrophic lateral sclerosis.

@nl

prefLabel

Stabilization of hyperdynamic ...... amyotrophic lateral sclerosis.

@en

Stabilization of hyperdynamic ...... amyotrophic lateral sclerosis.

@nl

P1433

Q46977479-A2CA1E8F-66BB-4F53-8C1D-673FFA9CE5FB

P1476

Q46977479-5F64AEE7-CDA0-4D4E-9600-CEEC614DEBC2

P2093

Q46977479-24E51B2A-73EE-4B2E-9312-8445B33FD80E

Q46977479-4F68F955-3525-4791-9260-9DBDE161A70B

Q46977479-5BEB7033-E428-4F56-A514-919B786AA7F5

Q46977479-7B7B5BCB-927C-4E28-8F43-ABC34F64A84B

Q46977479-96E1D66E-ACA2-4A60-8843-C862F5A8FCEB

Q46977479-9FC57267-A2AF-49E6-9520-4F0095C3CF0D

Q46977479-BB31E9CE-DE74-4FDE-9A88-27EF353DF9C8

Q46977479-E6ABF183-C706-4A72-BC10-6C4319F29CD2

Q46977479-FCC6833C-7E3C-43C2-B24C-A09613899914

P2860

Q46977479-03AC1E8F-6AD2-4C13-975D-52AD099534BA

Q46977479-086431AD-3DC0-44A7-B8DF-12B94C18B740

Q46977479-0A9908EA-74C7-4A94-BF83-E1B57809CE1A

Q46977479-187F4D86-EF3F-44DA-9FCF-35CC393C659A

Q46977479-35D34355-2B5F-4142-9B89-23074255CA0F

Q46977479-44C4ED5E-1FA0-4704-99E5-CAC48C301545

Q46977479-44E600A9-7393-4C8C-AEA1-BECF7CB8A315

Q46977479-47B0CCB8-177F-4BE2-AD05-0D328419BB31

Q46977479-49A260A6-C777-4DE7-A060-F42DD566768A

Q46977479-622CDF8E-7685-4561-BAE6-E465686BC63E

P304

Q46977479-7A220E65-0844-4829-9786-8EF1E69905F0

P31

Q46977479-4C83405E-7234-4789-87D4-55962A79453E

P356

Q46977479-A1BFAF10-9DFA-45F8-992F-7FB7B5C71754

P407

Q46977479-12B0936E-8BAE-4F18-A7BC-1E0D8ECD8F8A

P433

Q46977479-54269931-1129-473B-BCEB-8579A4DFEC5D

P478

Q46977479-D9491E67-F52F-480B-BA2D-D189BD6646E8

P577

Q46977479-C58A775C-0DC1-40D3-B9E6-3B5B706C9806

P698

Q46977479-AD64884B-216E-4495-9EB6-6541485BBB9F

P921

Q46977479-3F33427D-EA56-4FF6-B07D-469A9658AB25

P356

P1433

Journal of Biological Chemistry

P1476

Stabilization of hyperdynamic ...... amyotrophic lateral sclerosis.

@en

P2093

Holly Turner

http://www.w3.org/2001/XMLSchema#string

Jayee Banerjee

http://www.w3.org/2001/XMLSchema#string

Kristofor H Husted

http://www.w3.org/2001/XMLSchema#string

Macha R Harper

http://www.w3.org/2001/XMLSchema#string

Marc K Hellerstein

http://www.w3.org/2001/XMLSchema#string

Mohamad Awada

http://www.w3.org/2001/XMLSchema#string

Patrizia Fanara

http://www.w3.org/2001/XMLSchema#string

Roland Brandt

http://www.w3.org/2001/XMLSchema#string

Rommel V Hueck

http://www.w3.org/2001/XMLSchema#string

P2860

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

Stable tubule only polypeptides (STOP) proteins co-aggregate with spheroid neurofilaments in amyotrophic lateral sclerosis

Differential interactions of MAP2, tau and MAP5 during axogenesis in culture.

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded.

The cytoskeleton in neurodegenerative diseases.

Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis.

Do disorders of movement cause movement disorders and dementia?

P304

23465-23472

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M703434200

http://www.w3.org/2001/XMLSchema#string

P407

P433

32

http://www.w3.org/2001/XMLSchema#string

P478

282

http://www.w3.org/2001/XMLSchema#string

P577

2007-06-13T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

17567579

http://www.w3.org/2001/XMLSchema#string

P921

amyotrophic lateral sclerosis