KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier.
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Ion channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early chordatesPolarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domainsNeural KCNQ (Kv7) channelsAn ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathyNew molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channelsMolecular targets for antiepileptic drug developmentMechanisms of sodium channel clustering and its influence on axonal impulse conductionTwo-pore domain potassium channels enable action potential generation in the absence of voltage-gated potassium channelsNode of Ranvier disruption as a cause of neurological diseasesDriving with no brakes: molecular pathophysiology of Kv7 potassium channelsStructure and Sodium Channel Activity of an Excitatory I 1 -Superfamily Conotoxin † , ‡Axonal Dysfunction Precedes Motor Neuronal Death in Amyotrophic Lateral SclerosisK(V)7/KCNQ channels are functionally expressed in oligodendrocyte progenitor cellsClinical, genetic, neurophysiological and functional study of new mutations in episodic ataxia type 1.Converging on the origins of axonal ion channel clustering.Isoform-specific prolongation of Kv7 (KCNQ) potassium channel opening mediated by new molecular determinants for drug-channel interactionsIH activity is increased in populations of slow versus fast motor axons of the ratClustered K+ channel complexes in axonsDevelopmental expression of Kv potassium channels at the axon initial segment of cultured hippocampal neuronsComposition, assembly, and maintenance of excitable membrane domains in myelinated axons.Made for "anchorin": Kv7.2/7.3 (KCNQ2/KCNQ3) channels and the modulation of neuronal excitability in vertebrate axons.Beyond faithful conduction: short-term dynamics, neuromodulation, and long-term regulation of spike propagation in the axon.Contributions of Kv7-mediated potassium current to sub- and suprathreshold responses of rat layer II/III neocortical pyramidal neurons.BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells.Kv7.2 regulates the function of peripheral sensory neurons.Kv7.5 is the primary Kv7 subunit expressed in C-fibers.Activation of peripheral KCNQ channels relieves gout pain.Molecular microdomains in a sensory terminal, the vestibular calyx endingThe Temporal Profiles of Changes in Nerve Excitability Indices in Familial Amyloid Polyneuropathy.Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain.An Ankyrin-G N-terminal Gate and Protein Kinase CK2 Dually Regulate Binding of Voltage-gated Sodium and KCNQ2/3 Potassium ChannelsDopamine modulation of Ih improves temporal fidelity of spike propagation in an unmyelinated axonA distinct three-helix centipede toxin SSD609 inhibits I(ks) channels by interacting with the KCNE1 auxiliary subunit.Calcium-Activated Potassium Channels at Nodes of Ranvier Secure Axonal Spike Propagation.In vivo loss of slow potassium channel activity in individuals with benign familial neonatal epilepsy in remissionCombinatorial augmentation of voltage-gated KCNQ potassium channels by chemical openers.Impaired Axonal Na(+) Current by Hindlimb Unloading: Implication for Disuse Neuromuscular Atrophy.Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of K(v)7.2 potassium channel subunits.Activation of axonal Kv7 channels in human peripheral nerve by flupirtine but not placebo - therapeutic potential for peripheral neuropathies: results of a randomised controlled trial.Coupling of L-type Ca2+ channels to KV7/KCNQ channels creates a novel, activity-dependent, homeostatic intrinsic plasticity.
P2860
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P2860
KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
KCNQ channels mediate IKs, a s ...... ty in the rat node of Ranvier.
@en
KCNQ channels mediate IKs, a s ...... ty in the rat node of Ranvier.
@nl
type
label
KCNQ channels mediate IKs, a s ...... ty in the rat node of Ranvier.
@en
KCNQ channels mediate IKs, a s ...... ty in the rat node of Ranvier.
@nl
prefLabel
KCNQ channels mediate IKs, a s ...... ty in the rat node of Ranvier.
@en
KCNQ channels mediate IKs, a s ...... ty in the rat node of Ranvier.
@nl
P2093
P2860
P1476
KCNQ channels mediate IKs, a s ...... ty in the rat node of Ranvier.
@en
P2093
E C Cooper
G Glassmeier
J R Schwarz
P2860
P356
10.1113/JPHYSIOL.2006.106815
P407
P577
2006-03-09T00:00:00Z