Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. - Wikidata - wikimedia - TriplyDB

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb.

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb.

http://www.wikidata.org/entity/Q47070747

about

Wnt signaling pathways in urological cancers: past decades and still growing An initial biochemical and cell biological characterization of the mammalian homologue of a central plant developmental switch, COP1.Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP Identification of the receptor component of the IkappaBalpha-ubiquitin ligase DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex A genetic screen in Drosophila for identifying novel components of the hedgehog signaling pathway.Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity Wnt/beta-catenin signaling and small molecule inhibitors Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34 The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK Wnt signaling: the good and the bad Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells Involvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in Drosophila Downregulation of peroxisome proliferator-activated receptors (PPARs) in nasal polyposis Differential range and activity of various forms of the Hedgehog protein Protective roles of free avian respiratory macrophages in captive birds Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis Toggling a conformational switch in Wnt/β-catenin signaling: regulation of Axin phosphorylation. The phosphorylation state of Axin controls its scaffold function in two Wnt pathway protein complexes The effects of dietary polyphenols on reproductive health and early development PPAR-γ -- a possible drug target for complicated pregnancies The case for intraocular delivery of PPAR agonists in the treatment of diabetic retinopathy Primary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengers Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity Decoding the phosphorylation code in Hedgehog signal transduction Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases Intravenous multipotent adult progenitor cell treatment decreases inflammation leading to functional recovery following spinal cord injury.Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation Crystal Structure of a Full-Length β-Catenin

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Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb.

http://www.wikidata.org/entity/Q47070747

description

1998 nî lūn-bûn

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1998年の論文

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年學術文章

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1998年學術文章

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name

Regulation of the Hedgehog and ...... box/WD40-repeat protein Slimb.

@en

Regulation of the Hedgehog and ...... box/WD40-repeat protein Slimb.

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type

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Regulation of the Hedgehog and ...... box/WD40-repeat protein Slimb.

@en

Regulation of the Hedgehog and ...... box/WD40-repeat protein Slimb.

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prefLabel

Regulation of the Hedgehog and ...... box/WD40-repeat protein Slimb.

@en

Regulation of the Hedgehog and ...... box/WD40-repeat protein Slimb.

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Regulation of the Hedgehog and ...... box/WD40-repeat protein Slimb.

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G Struhl

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J Jiang

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P2860

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p.

Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

Dual roles for patched in sequestering and transducing Hedgehog

beta-catenin is a target for the ubiquitin-proteasome pathway

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

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