Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.
about
Prader-Willi, Angelman, and 15q11-q13 Duplication SyndromesEpigenetic regulation of UBE3A and roles in human neurodevelopmental disorders.Quantitative proteomic analysis of Parkin substrates in Drosophila neurons.Gene expression analysis of human induced pluripotent stem cell-derived neurons carrying copy number variants of chromosome 15q11-q13.1.Case of 7p22.1 Microduplication Detected by Whole Genome Microarray (REVEAL) in Workup of Child Diagnosed with AutismProteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells.Peptides in headlock--a novel high-affinity and versatile peptide-binding nanobody for proteomics and microscopy.Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkagesAngelman syndrome-associated ubiquitin ligase UBE3A/E6AP mutants interfere with the proteolytic activity of the proteasome.Do Low Serum UCH-L1 and TDP-43 Levels Indicate Disturbed Ubiquitin-Proteosome System in Autism Spectrum Disorder?The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome.Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer.Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons.Proteotranscriptomic measurements of E6-Associated Protein (E6AP) targets in DU145 prostate cancer cells.Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes.Isolation of Ubiquitinated Proteins to High Purity from In Vivo Samples.Insights into the ubiquitin-proteasome system of human embryonic stem cells.Neuronal Proteomic Analysis of the Ubiquitinated Substrates of the Disease-Linked E3 Ligases Parkin and Ube3a.Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.Subcellular organization of UBE3A in human cerebral cortex
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Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.
description
2013 nî lūn-bûn
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name
Ube3a, the E3 ubiquitin ligase ...... the proteasomal shuttle Rpn10.
@en
Ube3a, the E3 ubiquitin ligase ...... the proteasomal shuttle Rpn10.
@nl
type
label
Ube3a, the E3 ubiquitin ligase ...... the proteasomal shuttle Rpn10.
@en
Ube3a, the E3 ubiquitin ligase ...... the proteasomal shuttle Rpn10.
@nl
prefLabel
Ube3a, the E3 ubiquitin ligase ...... the proteasomal shuttle Rpn10.
@en
Ube3a, the E3 ubiquitin ligase ...... the proteasomal shuttle Rpn10.
@nl
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Ube3a, the E3 ubiquitin ligase ...... the proteasomal shuttle Rpn10
@en
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Maribel Franco
So Young Lee
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10.1007/S00018-013-1526-7
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2013-12-01T00:00:00Z