Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways.
about
The dynamic cilium in human diseasesA novel protein LZTFL1 regulates ciliary trafficking of the BBSome and SmoothenedIndividuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathyLoss-of-function mutations in LRRC6, a gene essential for proper axonemal assembly of inner and outer dynein arms, cause primary ciliary dyskinesiaZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6Nephrocystin-3 is required for ciliary function in zebrafish embryosHearing in Drosophila requires TilB, a conserved protein associated with ciliary motilityThe primary cilium as a cellular signaling center: lessons from diseaseGenetic factors contributing to human primary ciliary dyskinesia and male infertilityThe exocyst protein Sec10 interacts with Polycystin-2 and knockdown causes PKD-phenotypesThe ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signalingImpaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathyModelling a ciliopathy: Ahi1 knockdown in model systems reveals an essential role in brain, retinal, and renal developmentThe coiled-coil domain containing protein CCDC151 is required for the function of IFT-dependent motile cilia in animalsSmall heat shock proteins are necessary for heart migration and laterality determination in zebrafish.Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene.Mutations in zebrafish leucine-rich repeat-containing six-like affect cilia motility and result in pronephric cysts, but have variable effects on left-right patterning.Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathwayLoss of oriented cell division does not initiate cyst formationThe ATP-sensitive K(+)-channel (K(ATP)) controls early left-right patterning in Xenopus and chick embryos.The N-terminal region of centrosomal protein 290 (CEP290) restores vision in a zebrafish model of human blindness.Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning.Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility.NudC regulates actin dynamics and ciliogenesis by stabilizing cofilin 1.Primary cilia are not required for normal canonical Wnt signaling in the mouse embryo.Zebrafish Models of Kidney Damage and RepairPrimary cilia regulate branching morphogenesis during mammary gland development.Qilin is essential for cilia assembly and normal kidney development in zebrafishZebrafish Nkd1 promotes Dvl degradation and is required for left-right patterningConditional expression of Wnt9b in Six2-positive cells disrupts stomach and kidney functionMultiple renal cyst development but not situs abnormalities in transgenic RNAi mice against Inv::GFP rescue genePronephric tubulogenesis requires Daam1-mediated planar cell polarity signaling.IFT46 plays an essential role in cilia developmentc-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis.nlz1 is required for cilia formation in zebrafish embryogenesis.Cilia, Wnt signaling, and the cytoskeletonc21orf59/kurly Controls Both Cilia Motility and PolarizationMicropatterning of cells reveals chiral morphogenesis.Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy.
P2860
Q21202039-A53429C5-32FE-45E8-8C73-72BA5EAD51CBQ24296671-F053E4F0-1E5E-4099-9718-45E2718A82B5Q24300810-6246CD14-4FF2-4E1C-B441-6F11FA711754Q24302252-CD049E4D-932D-4B0F-BDA7-C4F13F1A7688Q24312017-A66CD143-195E-4D89-8DFA-F9A5D3B23D6CQ24312027-105AFA53-E3D5-4039-B170-FC0BD25051FEQ24616886-C4870BC7-6665-41FB-B4AA-5AC69034AEBFQ24632942-A0CA074A-6BED-438D-BD06-C8276E03F2DAQ26748534-47373494-E7B0-44D1-B0E9-5BE60593B59CQ27342580-574AE110-A87B-44CA-A5BD-76B291A6DF13Q28116639-E81A3619-71F6-428E-BA18-17D913329661Q28506100-F0A12477-873E-462C-A7EE-7A9753353443Q28506685-0422172E-A6ED-4425-90B9-030DA33AA425Q28589999-1B4176B1-A302-4564-B3FD-89B83903D835Q28659102-670D46CA-3B6E-4BF2-ACD8-354823B65414Q30485917-A1557000-4BC0-478D-A98F-BDF11C3762F0Q30487245-3E48ACBF-EF12-4593-99EE-82E8726AA726Q30489319-7949AF46-F331-48E9-A516-4B59F614492DQ30493527-752BCD39-1FA8-48B3-A057-50BF9D7DE72BQ30496547-0F089BC8-E799-402E-AD05-54C603CFE410Q30499095-67CA24F3-B914-463E-9EFE-DA831586B0ABQ30499162-81829CB3-B6D3-4290-8FC9-98318DF05384Q30542132-829B1CC2-6A0C-4126-A763-4FECE3B916B8Q30708629-E600A248-8C08-4CE1-842F-125EE5519D9DQ33498502-322C849B-C867-443F-8CEE-0B31DFB0B072Q33873250-DF18B020-7610-44B6-A40D-D26C391AFAF8Q34047857-F234F318-235C-4D13-9821-017C6596D0BBQ34079279-23501B29-8BEF-47E6-B403-222509534001Q34139282-704FD063-D1E7-4A63-BD49-1A0E8F3EB5EEQ34389279-3B6997C0-9E7C-42D0-8E92-C5BD674567E0Q35107829-3DCAC1BF-4A37-427F-A8DF-702B3ABA09B2Q35210200-C40B2D6E-EF8D-42A6-AFF7-3A1916C709D1Q35269398-1F896980-7D06-44A9-8A61-B27F334D56F0Q36109160-EDC67CD4-6261-4E1B-A88D-E95A82A6C436Q36220813-B8B68C1E-4A20-4462-9488-EA94C2885987Q36264739-5F27E820-CCF0-42A6-B444-0407B77C4319Q36564463-1198BCB3-0445-4145-B6F1-B814C9B5F85AQ36643007-BDAA1B62-5752-4E36-B5FA-6B36BFCF9887Q36998279-BB7FA4C5-06FC-447B-BEA6-6F873A91CD9DQ37111349-5EAC7FCB-E79C-4E56-88EB-9183BF97044F
P2860
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways.
@en
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways.
@nl
type
label
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways.
@en
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways.
@nl
prefLabel
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways.
@en
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways.
@nl
P2093
P1433
P1476
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways.
@en
P2093
Alice Park
Norihito Kishimoto
Zhaoxia Sun
P304
P356
10.1016/J.DEVCEL.2008.03.010
P407
P577
2008-06-01T00:00:00Z