Generation of tryptophan hydroxylase 2 gene knockout pigs by CRISPR/Cas9-mediated gene targeting.

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Generation of tryptophan hydroxylase 2 gene knockout pigs by CRISPR/Cas9-mediated gene targeting.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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Generation of tryptophan hydro ...... /Cas9-mediated gene targeting.

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Generation of tryptophan hydro ...... /Cas9-mediated gene targeting.

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Generation of tryptophan hydro ...... /Cas9-mediated gene targeting.

@en

Generation of tryptophan hydro ...... /Cas9-mediated gene targeting.

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Generation of tryptophan hydro ...... /Cas9-mediated gene targeting.

@en

Generation of tryptophan hydro ...... /Cas9-mediated gene targeting.

@nl

P1476

Generation of tryptophan hydro ...... /Cas9-mediated gene targeting.

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P2093

Hai-Yuan Yang

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Li-Ning Zhang

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Li-Sha Mou

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Man-Ling Zhang

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Qiang Xiong

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Rong-Feng Li

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Xiao-Rui Liu

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Yan Liu

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Yi Rao

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Yi-Fan Dai

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P2860

Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.

Initial sequencing and comparative analysis of the mouse genome

Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function

Growth retardation and altered autonomic control in mice lacking brain serotonin

Efficient Generation of Myostatin Knock-Out Sheep Using CRISPR/Cas9 Technology and Microinjection into Zygotes

Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin

A unique central tryptophan hydroxylase isoform

Synthesis of serotonin by a second tryptophan hydroxylase isoform

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

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445-452

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scholarly article

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10.7555/JBR.31.20170026

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P433

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P478

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P577

2017-09-03T00:00:00Z

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P698

28866660

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P921

CRISPR

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5706437

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