Lenalidomide overcomes the immunosuppression of regulatory CD8+CD28- T-cells.

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Lenalidomide overcomes the immunosuppression of regulatory CD8+CD28- T-cells.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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2017年學術文章

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Lenalidomide overcomes the immunosuppression of regulatory CD8+CD28- T-cells.

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Lenalidomide overcomes the immunosuppression of regulatory CD8+CD28- T-cells.

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Lenalidomide overcomes the immunosuppression of regulatory CD8+CD28- T-cells.

@en

Lenalidomide overcomes the immunosuppression of regulatory CD8+CD28- T-cells.

@nl

prefLabel

Lenalidomide overcomes the immunosuppression of regulatory CD8+CD28- T-cells.

@en

Lenalidomide overcomes the immunosuppression of regulatory CD8+CD28- T-cells.

@nl

P1476

Lenalidomide overcomes the immunosuppression of regulatory CD8+CD28- T-cells.

@en

P2093

Brigitte Neuber

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Jingying Dai

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Mathias Witzens-Harig

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Melanie Engelhardt

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Michael Hundemer

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Michael Schmitt

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Mohamed H S Awwad

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Sergej Medenhoff

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Wjahat A Waraich

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P2860

Identification of a primary target of thalidomide teratogenicity

Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins

A phase 2, randomized, double-blind, placebo-controlled study of siltuximab (anti-IL-6 mAb) and bortezomib versus bortezomib alone in patients with relapsed or refractory multiple myeloma.

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide.

FOXP3 and CTLA4 overexpression in multiple myeloma bone marrow as a sign of accumulation of CD4(+) T regulatory cells.

Increased T regulatory cells are associated with adverse clinical features and predict progression in multiple myeloma.

Lenalidomide and thalidomide: mechanisms of action--similarities and differences.

Human CD4+CD25+ regulatory T cells are sensitive to low dose cyclophosphamide: implications for the immune response.

Phenotypical and functional alterations of CD8 regulatory T cells in primary biliary cirrhosis.

P304

98200-98214

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P31

scholarly article

P356

10.18632/ONCOTARGET.21516

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Hartmut Goldschmidt

Anthony D Ho

P577

2017-10-05T00:00:00Z

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P698

29228683

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P921

immunosuppression

P932

5716723

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