Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression.

about

When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies.Up-regulated deubiquitinase USP4 plays an oncogenic role in melanoma.

P2860

Q51763128-FD701472-A25D-4C82-B1C2-ABAEDD159810 Q52654685-8BC248B9-588E-4E1F-A7B5-C189EF538B6B

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Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression.

Item

http://www.wikidata.org/entity/Q47132104

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

Parkin targets HIF-1α for ubiq ...... ibit breast tumor progression.

@en

Parkin targets HIF-1α for ubiq ...... ibit breast tumor progression.

@nl

type

Item

label

Parkin targets HIF-1α for ubiq ...... ibit breast tumor progression.

@en

Parkin targets HIF-1α for ubiq ...... ibit breast tumor progression.

@nl

prefLabel

Parkin targets HIF-1α for ubiq ...... ibit breast tumor progression.

@en

Parkin targets HIF-1α for ubiq ...... ibit breast tumor progression.

@nl

P1476

Parkin targets HIF-1α for ubiq ...... hibit breast tumor progression

@en

P2093

Bruce G Haffty

http://www.w3.org/2001/XMLSchema#string

Cen Zhang

http://www.w3.org/2001/XMLSchema#string

Christen A Khella

http://www.w3.org/2001/XMLSchema#string

Dajing Xia

http://www.w3.org/2001/XMLSchema#string

Haiyang Xie

http://www.w3.org/2001/XMLSchema#string

Hao Wu

http://www.w3.org/2001/XMLSchema#string

James Chen

http://www.w3.org/2001/XMLSchema#string

Jimin Gao

http://www.w3.org/2001/XMLSchema#string

Juan Liu

http://www.w3.org/2001/XMLSchema#string

Kyle Tomsky

http://www.w3.org/2001/XMLSchema#string

P2860

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

Autoregulation of Parkin activity through its ubiquitin-like domain

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

How does parkin ligate ubiquitin to Parkinson's disease?

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

P2888

s41467-017-01947-w

P304

1823

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/S41467-017-01947-W

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Yuhan Zhao

Eileen White

Michael L Gatza

P577

2017-11-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29180628

http://www.w3.org/2001/XMLSchema#string

P921

protein ubiquitination

P932

5703960

http://www.w3.org/2001/XMLSchema#string

Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression.

about

P2860

P2860

Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression.

description

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type

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P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932