The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY.
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The 2018 Nucleic Acids Research database issue and the online molecular biology database collection.GPCRdb in 2018: adding GPCR structure models and ligands.Fixed dosing of intravenous tocilizumab in rheumatoid arthritis. Results from a population pharmacokinetic analysis.Partial rescue of F508del-CFTR channel gating with modest improvement of protein processing, but not stability by a dual-acting small molecule.The 2018 Nucleic Acids Research database issue and the online molecular biology database collection.The soluble guanylate cyclase stimulator IW-1973 prevents inflammation and fibrosis in experimental non-alcoholic steatohepatitis.Role of signaling molecules in behaviors mediated by the δ-receptor agonist SNC80.Different contribution of chemokine N-terminal features attest a different ligand binding mode and a bias towards activation of the atypical chemokine receptor ACKR3/CXCR7 compared to CXCR4 and CXCR3.GSH-PEGylated liposomal methylprednisolone in comparison to free methylprednisolone: slow release characteristics and prolonged lymphocyte depression in a first-in-human study.Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function.Clinical impact of pharmacokinetic interactions between the HCV protease inhibitor Simeprevir and frequently used concomitant medications.The use of chemogenetics in behavioural neuroscience: Receptor variants, targeting approaches, and caveats.Acute ethanol exposure has bidirectional actions on the endogenous neuromodulator adenosine in rat hippocampus.Sophocarpine attenuates wear particle-induced implant loosening by inhibiting osteoclastogenesis and bone resorption via suppression of the NF-κB signaling pathway in a rat model.The effect of itraconazole and rifampicin on the pharmacokinetics of osimertinib.Prophylactic benefits of systemically delivered simvastatin treatment in a house dust mite challenged murine model of allergic asthma.No pain, no gain: balancing central versus peripheral benefits of analgesics in the age of the opioid crisis.The current state of GPCR-based drug discovery to treat metabolic disease.Time-to-event modelling of effect of codrituzumab on overall survival in patients with hepatocellular carcinoma.In Vivo Effects of μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Peptidomimetics Following Acute and Repeated Administration.Proton-independent activation of acid-sensing ion channel ASIC3 by alkaloid lindoldhamine from Laurus nobilis.Bumetanide blocks the acquisition of conditioned fear in adult rats.Functional interplay between LXR and AMPKα inhibits atherosclerosis in apoE deficient mice - A new anti-atherogenic strategy.A Natural Compound Formononetin Derived From Astragalus Membranaceus Increase Adipocyte Thermogenesis by Modulating PPARγ Activity.Discontinuities and disruptions in drug dosage guidelines for the paediatric population.CRF2 receptor-deficiency eliminates social behaviour deficits and vulnerability induced by cocaine.Anti-inflammatory therapies in myocardial infarction: failures, hopes, and challenges.The pharmacodynamic and clinical trial evidence for statin dose.Argon attenuates multiorgan failure following experimental aortic cross-clamping.A clinically relevant decrease in abiraterone exposure associated with carbamazepine use in a patient with castration-resistant metastatic prostate cancer.Balancing early access with uncertainties in evidence for drugs authorized by prospective case series - systematic review of reimbursement decisions.Developmental pharmacogenetics of CYP2C19 in neonates and young infants: omeprazole as a probe drug.Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain.Resolvin E1, resolvin D1 and resolvin D2 inhibit constriction of rat thoracic aorta and human pulmonary artery induced by the thromboxane mimetic U46619.INFLUENCE OF PHARMACOGENETIC POLYMORPHISMS AND DEMOGRAPHIC VARIABLES ON METFORMIN PHARMACOKINETICS IN AN ADMIXED BRAZILIAN COHORT.First-in-human study to assess the safety, pharmacokinetics and pharmacodynamics of BMS-962212, a direct, reversible, small molecule factor XIa inhibitor in non-Japanese and Japanese healthy subjects.Pharmacokinetic/pharmacodynamic drug-drug interactions of avatrombopag when co-administered with dual or selective CYP2C9 and CYP3A interacting drugs.The impact of diuretic use and ABCG2 genotype on the predictive performance of a published allopurinol dosing tool.Better characterization of vinflunine pharmacokinetics variability and exposure/toxicity relationship to improve its use: analyses from 18 trials.Thrombospondin-4 acts on pre-synaptic calcium channel alpha-2-delta-1 subunit to induce synaptogenesis between sensory and spinal cord neurons through a T-type calcium channel dependent pathway that is blocked by early, low-dose gabapentin treatment
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The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年学术文章
@wuu
2017年学术文章
@zh
2017年学术文章
@zh-cn
2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
@zh-hant
name
The IUPHAR/BPS Guide to PHARMA ...... w guide to IMMUNOPHARMACOLOGY.
@en
The IUPHAR/BPS Guide to PHARMA ...... w guide to IMMUNOPHARMACOLOGY.
@nl
type
label
The IUPHAR/BPS Guide to PHARMA ...... w guide to IMMUNOPHARMACOLOGY.
@en
The IUPHAR/BPS Guide to PHARMA ...... w guide to IMMUNOPHARMACOLOGY.
@nl
altLabel
The IUPHAR/BPS Guide to PHARMA ...... ew guide to IMMUNOPHARMACOLOGY
@en
prefLabel
The IUPHAR/BPS Guide to PHARMA ...... w guide to IMMUNOPHARMACOLOGY.
@en
The IUPHAR/BPS Guide to PHARMA ...... w guide to IMMUNOPHARMACOLOGY.
@nl
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P2860
P50
P356
P1476
The IUPHAR/BPS Guide to PHARMA ...... ew guide to IMMUNOPHARMACOLOGY
@en
P2093
Christian Doerig
Clare Bryant
Doriano Fabbro
Francesca Levi-Schaffer
Jamie A Davies
Liam Bruce
Michael Spedding
Stephen Anderton
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P304
D1091-D1106
P356
10.1093/NAR/GKX1121
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P50
P577
2018-01-01T00:00:00Z