Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage explants ex vivo.

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Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage explants ex vivo.

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2017 nî lūn-bûn

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2017年学术文章

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Sprifermin (rhFGF18) modulates ...... in cartilage explants ex vivo.

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Item

label

Sprifermin (rhFGF18) modulates ...... in cartilage explants ex vivo.

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Sprifermin (rhFGF18) modulates ...... in cartilage explants ex vivo.

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P1476

Sprifermin (rhFGF18) modulates ...... in cartilage explants ex vivo.

@en

P2093

Anne C Bay-Jensen

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Anne Gigout

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Anne Sofie Siebuhr

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Cecilie F Kjelgaard-Petersen

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Christoph Ladel

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Ditte Reker

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Martin Michaelis

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Morten A Karsdal

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P2860

Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis

Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis

Suppression of MMP activity in bovine cartilage explants cultures has little if any effect on the release of aggrecanase-derived aggrecan fragments.

Changes in cartilage metabolism in arthritis are reflected by altered serum and synovial fluid levels of the cartilage proteoglycan aggrecan. Implications for pathogenesis.

Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease.

Identification of fibroblast growth factor-18 as a molecule to protect adult articular cartilage by gene expression profiling.

Bioactivity in an Aggrecan 32-mer Fragment Is Mediated via Toll-like Receptor 2.

Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity

Cartilage turnover reflected by metabolic processing of type II collagen: a novel marker of anabolic function in chondrocytes.

P2888

s12967-017-1356-8

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250

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scholarly article

P356

10.1186/S12967-017-1356-8

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P433

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P478

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P577

2017-12-12T00:00:00Z

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P6179

1099598010

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P698

29233174

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P921

extracellular matrix

cartilage

P932

5727954

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