about
Virtual target screening: validation using kinase inhibitors.Advances in fragment-based drug discovery platforms.Recent advances in the design and development of novel negative allosteric modulators of mGlu(5)A desirability function-based scoring scheme for selecting fragment-like class A aminergic GPCR ligands.Biophysical limits of protein-ligand binding.DockingApp: a user friendly interface for facilitated docking simulations with AutoDock Vina.Melting Point Distribution Analysis of Globally Approved and Discontinued Drugs: A Research for Improving the Chance of Success of Drug Design and Discovery.Ligand-receptor interaction platforms and their applications for drug discovery.Advances in multiparameter optimization methods for de novo drug design.The impact of binding thermodynamics on medicinal chemistry optimizations.Analyzing compound and project progress through multi-objective-based compound quality assessment.Molecular dynamics simulations and in silico peptide ligand screening of the Elk-1 ETS domain.Thermodynamics of ligand binding and efficiency.Validity of ligand efficiency metrics.Ligand efficiency metrics: why all the fuss?Study of binding thermodynamics in the optimization of BH3 mimetics.Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective.The role of ligand efficiency metrics in drug discovery.Assessing the lipophilicity of fragments and early hits.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Simple size-independent measure of ligand efficiency.
@en
Simple size-independent measure of ligand efficiency.
@nl
type
label
Simple size-independent measure of ligand efficiency.
@en
Simple size-independent measure of ligand efficiency.
@nl
prefLabel
Simple size-independent measure of ligand efficiency.
@en
Simple size-independent measure of ligand efficiency.
@nl
P356
P1476
Simple size-independent measure of ligand efficiency.
@en
P2093
J Willem M Nissink
P304
P356
10.1021/CI900094M
P577
2009-06-01T00:00:00Z