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Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus.The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach.Development of anti-infectives using phage display: biological agents against bacteria, viruses, and parasites.Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A.Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae.Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach.A new antibiotic with potent activity targets MscL.Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activityFlemingin-Type Prenylated Chalcones from the Sarawak Rainforest Plant Desmodium congestum.Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F.Synthesis of Norbornane Bisether Antibiotics via Silver-mediated Alkylation.Antibacterial Low Molecular Weight Cationic Polymers: Dissecting the Contribution of Hydrophobicity, Chain Length and Charge to ActivityMucin Binding Reduces Colistin Antimicrobial Activity.Structure-activity relationships for the binding of polymyxins with human α-1-acid glycoproteinDrug-binding energetics of human α-1-acid glycoprotein assessed by isothermal titration calorimetry and molecular docking simulations.Molecular Characterization of Lipopolysaccharide Binding to Human α-1-Acid GlycoproteinActivity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.An "Unlikely" Pair: The Antimicrobial Synergy of Polymyxin B in Combination with the Cystic Fibrosis Transmembrane Conductance Regulator Drugs KALYDECO and ORKAMBI.Cell- and biomarker-based assays for predicting nephrotoxicity.Truncated Latrunculins as Actin Inhibitors Targeting Plasmodium falciparum Motility and Host Cell Invasion.α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors.Plasma Protein Binding Structure-Activity Relationships Related to the N-Terminus of Daptomycin.Drug-drug plasma protein binding interactions of ivacaftor.Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity.Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cellsRamoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus.An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants.Synthesis of essramycin and comparison of its antibacterial activity.Efficient synthesis of anacardic acid analogues and their antibacterial activities.Identification of antitubercular benzothiazinone compounds by ligand-based design.Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria.Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agentsStructure aided design of chimeric antibioticsStructure-Function Studies of Polymyxin B LipononapeptidesGenome-Wide Off-Target Analysis in CRISPR-Cas9 Modified Mice and Their Offspring
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Johnny X Huang
@ast
Johnny X Huang
@en
Johnny X Huang
@es
Johnny X Huang
@nl
Johnny X Huang
@sl
type
label
Johnny X Huang
@ast
Johnny X Huang
@en
Johnny X Huang
@es
Johnny X Huang
@nl
Johnny X Huang
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altLabel
Johnny X. Huang Xiao Huang
@en
prefLabel
Johnny X Huang
@ast
Johnny X Huang
@en
Johnny X Huang
@es
Johnny X Huang
@nl
Johnny X Huang
@sl
P106
P21
P31
P496
0000-0003-3595-208X