about
A conceptual mathematical model of the dynamic self-organisation of distinct cellular organellesComputational lipidology: predicting lipoprotein density profiles in human blood plasmaAssessment of hepatic detoxification activity: proposal of an improved variant of the (13)c-methacetin breath testSEE: structured representation of scientific evidence in the biomedical domain using Semantic Web techniquesStructural biology of mammalian lipoxygenases: enzymatic consequences of targeted alterations of the protein structure.Metabolic Consequences of TGFb Stimulation in CulturedPrimary Mouse Hepatocytes Screened from Transcript Data with ModeScoreIdentifying MHC class I epitopes by predicting the TAP transport efficiency of epitope precursors.METANNOGEN: compiling features of biochemical reactions needed for the reconstruction of metabolic networks.Including metabolite concentrations into flux balance analysis: thermodynamic realizability as a constraint on flux distributions in metabolic networksAntimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysisFASIMU: flexible software for flux-balance computation series in large metabolic networks.Multi-locus stepwise regression: a haplotype-based algorithm for finding genetic associations applied to atopic dermatitis.Quantifying the contribution of the liver to glucose homeostasis: a detailed kinetic model of human hepatic glucose metabolismCardioNet: a human metabolic network suited for the study of cardiomyocyte metabolismNetwork-based assessment of the selectivity of metabolic drug targets in Plasmodium falciparum with respect to human liver metabolismEvaluation of 41 candidate gene variants for obesity in the EPIC-Potsdam cohort by multi-locus stepwise regression.Computer simulations suggest a key role of membranous nanodomains in biliary lipid secretion.Sequential metabolic phases as a means to optimize cellular output in a constant environment.Molecular dioxygen enters the active site of 12/15-lipoxygenase via dynamic oxygen access channelsThe relative importance of kinetic mechanisms and variable enzyme abundances for the regulation of hepatic glucose metabolism--insights from mathematical modeling.Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomesA kinetic model for lipoxygenases based on experimental data with the lipoxygenase of reticulocytes.Red cell creatine in term and preterm, adequate and small for gestational age newborns after normal pregnancy or risk conditions. I. Statistical analysis of creatine in various groups of newborns.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Mathematical analysis of enzymic reaction systems using optimization principles.Enzymatic features of the glucose metabolism in tumor cells.Hepatitis B virus HBx peptide 116-138 and proteasome activator PA28 compete for binding to the proteasome alpha4/MC6 subunit.Metannogen: annotation of biological reaction networks.Mathematical Modeling of Cellular Metabolism.Characterizing the N-terminal processing motif of MHC class I ligands.Kinetic evidences for facilitation of peptide channelling by the proteasome activator PA28.The proteasome inhibitor PI31 competes with PA28 for binding to 20S proteasomes.Regulation of liver metabolism by the endosomal GTPase Rab5.The speciation of the proteomeKinetic Modeling of the Mitochondrial Energy Metabolism of Neuronal Cells: The Impact of Reduced α-Ketoglutarate Dehydrogenase Activities on ATP Production and Generation of Reactive Oxygen Species.The stability and robustness of metabolic states: identifying stabilizing sites in metabolic networks.Kinetic modeling of human hepatic glucose metabolism in type 2 diabetes mellitus predicts higher risk of hypoglycemic events in rigorous insulin therapy.Physiology-based kinetic modeling of neuronal energy metabolism unravels the molecular basis of NAD(P)H fluorescence transients.The mechanism of inactivation of lipoxygenases by acetylenic fatty acids.The influence of the chloride currents on action potential firing and volume regulation of excitable cells studied by a kinetic model.
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description
Biochemiker
@de
biochemist
@en
hulumtues
@sq
onderzoeker
@nl
հետազոտող
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name
Hermann-Georg Holzhütter
@ast
Hermann-Georg Holzhütter
@de
Hermann-Georg Holzhütter
@en
Hermann-Georg Holzhütter
@es
Hermann-Georg Holzhütter
@nl
type
label
Hermann-Georg Holzhütter
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Hermann-Georg Holzhütter
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Hermann-Georg Holzhütter
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Hermann-Georg Holzhütter
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Hermann-Georg Holzhütter
@nl
altLabel
H G Holzhütter
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H Holzhütter
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H-G Holzhütter
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H. G. Holzhütter
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H. Holzhütter
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H.-G. Holzhütter
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HG Holzhütter
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Holzhütter H
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Holzhütter H-G
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Holzhütter H.
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prefLabel
Hermann-Georg Holzhütter
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Hermann-Georg Holzhütter
@de
Hermann-Georg Holzhütter
@en
Hermann-Georg Holzhütter
@es
Hermann-Georg Holzhütter
@nl
P214
P106
P108
P1556
holzhutter.hermann-georg
P21
P214
P31
P4872
P496
0000-0002-5054-6023