Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter.
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Use of preclinical models to improve treatment of retinoblastoma.Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosisTranscriptional activity of the paired-like homeodomain proteins CHX10 and VSX1Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In VivoNuclear export is evolutionarily conserved in CVC paired-like homeobox proteins and influences protein stability, transcriptional activation, and extracellular secretion.Absence of chx10 causes neural progenitors to persist in the adult retinaCoexpression of normally incompatible developmental pathways in retinoblastoma genesisgamma-Protocadherins regulate neuronal survival but are dispensable for circuit formation in retinaVsx2 in the zebrafish retina: restricted lineages through derepression.Rax-CreERT2 knock-in mice: a tool for selective and conditional gene deletion in progenitor cells and radial glia of the retina and hypothalamus.Compensation by tumor suppressor genes during retinal development in mice and humans.Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a.Individual retinal progenitor cells display extensive heterogeneity of gene expression.Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidanceMüller cell activation, proliferation and migration following laser injuryPerturbations of microRNA function in mouse dicer mutants produce retinal defects and lead to aberrant axon pathfinding at the optic chiasm.The transcription factor RBP-J is essential for retinal cell differentiation and lamination.Effect of reduced retinal VLC-PUFA on rod and cone photoreceptorsDicer is required for the transition from early to late progenitor state in the developing mouse retina.Pax6a and Pax6b are required at different points in neuronal progenitor cell proliferation during zebrafish photoreceptor regeneration.Functional dissection of the role of UHRF1 in the regulation of retinoblastoma methylome.A transgenic mouse line expressing cre recombinase in undifferentiated postmitotic mouse retinal bipolar cell precursorsInduction of the ganglion cell differentiation program in human retinal progenitors before cell cycle exit.Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.Generation of an Rx-tTA: TetOp-Cre knock-in mouse line for doxycycline regulated Cre activity in the Rx expression domainChx10 is required to block photoreceptor differentiation but is dispensable for progenitor proliferation in the postnatal retina.Generation of mRx-Cre transgenic mouse line for efficient conditional gene deletion in early retinal progenitors.Genetic modulation of horizontal cell number in the mouse retina.Cell-specific cre recombinase expression allows selective ablation of glutamate receptors from mouse horizontal cells.Wnt ligands from the embryonic surface ectoderm regulate 'bimetallic strip' optic cup morphogenesis in mouseNotch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property.The TAg-RB murine retinoblastoma cell of origin has immunohistochemical features of differentiated Muller glia with progenitor properties.Alternative splicing of the LIM-homeodomain transcription factor Isl1 in the mouse retina.Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Müller glial cell development.Development and neurogenic potential of Müller glial cells in the vertebrate retina.Expression and cellular localization of the voltage-gated calcium channel α2δ3 in the rodent retina.Cell autonomy of DSCAM function in retinal developmentRetinoblastoma (Rb) regulates laminar dendritic arbor reorganization in retinal horizontal neuronsGenetic chimeras reveal the autonomy requirements for Vsx2 in embryonic retinal progenitor cells.PTEN regulates retinal interneuron morphogenesis and synaptic layer formation.
P2860
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P2860
Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Genetic analysis of the homeod ...... BAC transgenic mouse reporter.
@en
Genetic analysis of the homeod ...... BAC transgenic mouse reporter.
@nl
type
label
Genetic analysis of the homeod ...... BAC transgenic mouse reporter.
@en
Genetic analysis of the homeod ...... BAC transgenic mouse reporter.
@nl
prefLabel
Genetic analysis of the homeod ...... BAC transgenic mouse reporter.
@en
Genetic analysis of the homeod ...... BAC transgenic mouse reporter.
@nl
P1476
Genetic analysis of the homeod ...... BAC transgenic mouse reporter.
@en
P2093
Constance L Cepko
Sheldon Rowan
P304
P356
10.1016/J.YDBIO.2004.03.039
P407
P577
2004-07-01T00:00:00Z