Intra- and intermolecular domain interactions of the C-terminal GTPase effector domain of the multimeric dynamin-like GTPase Drp1.
about
Control of mitochondrial morphology through differential interactions of mitochondrial fusion and fission proteinsNMR derived model of GTPase effector domain (GED) self association: relevance to dynamin assemblyMITD1 is recruited to midbodies by ESCRT-III and participates in cytokinesisMembrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerizationHuman MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fissionAtlastin GTPases are required for Golgi apparatus and ER morphogenesis.SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stressSUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycleLeucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like proteinMitochondrial dysfunction in inflammatory bowel diseaseFunctional Mapping of Human Dynamin-1-Like GTPase Domain Based on X-ray Structure AnalysesS-nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegenerationDnm1 forms spirals that are structurally tailored to fit mitochondria.Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexesA designed point mutant in Fis1 disrupts dimerization and mitochondrial fissionMitochondria-specific function of the dynamin family protein DLP1 is mediated by its C-terminal domainsMitochondrial dynamics in diabetic cardiomyopathyA mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathyS-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injuryBax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell deathThe mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse.Dynamin-related protein 1 (Drp1) promotes structural intermediates of membrane divisionMitochondrial fragmentation is involved in methamphetamine-induced cell death in rat hippocampal neural progenitor cells.Diabetes regulates mitochondrial biogenesis and fission in mouse neurons.In vivo functions of Drp1: lessons learned from yeast genetics and mouse knockoutsInhibition of mitochondrial division through covalent modification of Drp1 protein by 15 deoxy-Delta(12,14)-prostaglandin J2.S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease.CDK5-dependent inhibitory phosphorylation of Drp1 during neuronal maturationPreventing Ca2+-mediated nitrosative stress in neurodegenerative diseases: possible pharmacological strategies.A lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division.Morphological dynamics of mitochondria--a special emphasis on cardiac muscle cells.GSK3beta-mediated Drp1 phosphorylation induced elongated mitochondrial morphology against oxidative stress.Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli.Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson diseaseInteraction of the SPG21 protein ACP33/maspardin with the aldehyde dehydrogenase ALDH16A1.Dynamin-related protein 1 as a therapeutic target in cardiac arrestMitochondrial dynamics in pulmonary arterial hypertension.The mechanoenzymatic core of dynamin-related protein 1 comprises the minimal machinery required for membrane constriction.Pex11mediates peroxisomal proliferation by promoting deformation of the lipid membrane.Emerging functions of mammalian mitochondrial fusion and fission.
P2860
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P2860
Intra- and intermolecular domain interactions of the C-terminal GTPase effector domain of the multimeric dynamin-like GTPase Drp1.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Intra- and intermolecular doma ...... eric dynamin-like GTPase Drp1.
@en
Intra- and intermolecular doma ...... eric dynamin-like GTPase Drp1.
@nl
type
label
Intra- and intermolecular doma ...... eric dynamin-like GTPase Drp1.
@en
Intra- and intermolecular doma ...... eric dynamin-like GTPase Drp1.
@nl
prefLabel
Intra- and intermolecular doma ...... eric dynamin-like GTPase Drp1.
@en
Intra- and intermolecular doma ...... eric dynamin-like GTPase Drp1.
@nl
P2093
P2860
P356
P1476
Intra- and intermolecular doma ...... eric dynamin-like GTPase Drp1.
@en
P2093
Craig Blackstone
Daniel P Seeburg
Julia Stadler
Morgan Sheng
Peng-Peng Zhu
P2860
P304
35967-35974
P356
10.1074/JBC.M404105200
P407
P577
2004-06-18T00:00:00Z