Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci.

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The Current State and Future of CRISPR-Cas9 gRNA Design Tools Disruption by SaCas9 Endonuclease of HERV-K, a Retroviral Gene with Oncogenic and Neuropathogenic Potential, Inhibits Molecules Involved in Cancer and Amyotrophic Lateral Sclerosis

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Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci.

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http://www.wikidata.org/entity/Q47327388

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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Human genetic variation alters ...... erapeutically implicated loci.

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Human genetic variation alters ...... erapeutically implicated loci.

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Human genetic variation alters ...... erapeutically implicated loci.

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Human genetic variation alters ...... erapeutically implicated loci.

@nl

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Human genetic variation alters ...... erapeutically implicated loci.

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Human genetic variation alters ...... erapeutically implicated loci.

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Human genetic variation alters ...... erapeutically implicated loci.

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Daniel G MacArthur

http://www.w3.org/2001/XMLSchema#string

Guillaume Lettre

http://www.w3.org/2001/XMLSchema#string

Jean-Claude Tardif

http://www.w3.org/2001/XMLSchema#string

Jessica Alfoldi

http://www.w3.org/2001/XMLSchema#string

Laurent Francioli

http://www.w3.org/2001/XMLSchema#string

Patrick T Ellinor

http://www.w3.org/2001/XMLSchema#string

Samuel Lessard

http://www.w3.org/2001/XMLSchema#string

Stuart H Orkin

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P2860

Variation in genome-wide mutation rates within and between human families

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A global reference for human genetic variation

Genome-editing Technologies for Gene and Cell Therapy

CRISPR/Cas9 and cancer targets: future possibilities and present challenges

Analysis of protein-coding genetic variation in 60,706 humans

Off-target Effects in CRISPR/Cas9-mediated Genome Engineering

Therapeutic genome editing: prospects and challenges

In vivo genome editing restores haemostasis in a mouse model of haemophilia

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections

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E11257-E11266

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scholarly article

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10.1073/PNAS.1714640114

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English

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114

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Matthew C Canver

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2017-12-11T00:00:00Z

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29229813

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P921

CRISPR

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5748207

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Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci.

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P2860

P2860

Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci.

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type

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932