PERK leads a hub dictating pancreatic β cell homoeostasis.

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PERK leads a hub dictating pancreatic β cell homoeostasis.

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2017 nî lūn-bûn

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2017年学术文章

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PERK leads a hub dictating pancreatic β cell homoeostasis.

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PERK leads a hub dictating pancreatic β cell homoeostasis.

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PERK leads a hub dictating pancreatic β cell homoeostasis.

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PERK leads a hub dictating pancreatic β cell homoeostasis.

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PERK leads a hub dictating pancreatic β cell homoeostasis.

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PERK leads a hub dictating pancreatic β cell homoeostasis.

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P1476

PERK leads a hub dictating pancreatic β cell homoeostasis.

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P2093

George Kefalas

http://www.w3.org/2001/XMLSchema#string

Louise Larose

http://www.w3.org/2001/XMLSchema#string

P2860

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival

Perk is essential for translational regulation and cell survival during the unfolded protein response

EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

Regulated translation initiation controls stress-induced gene expression in mammalian cells

Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

P304

27-32

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P31

scholarly article

P356

10.1111/BOC.201700059

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P433

http://www.w3.org/2001/XMLSchema#string

P478

110

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P50

Louise Larose

George Kefalas

P577

2017-11-23T00:00:00Z

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P698

29168198

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