Propofol is an allosteric agonist with multiple binding sites on concatemeric ternary GABAA receptors.

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High constitutive activity accounts for the combination of enhanced direct activation and reduced potentiation in mutated GABAA receptors.Possible neurotoxicity of the anesthetic propofol: evidence for the inhibition of complex II of the respiratory chain in area CA3 of rat hippocampal slices

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Q50035831-52B68F7C-80C7-4CD2-B0CE-509A00BE645D Q58704744-BCC35E66-69FE-43F6-AA13-F8119943BBF2

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Propofol is an allosteric agonist with multiple binding sites on concatemeric ternary GABAA receptors.

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http://www.wikidata.org/entity/Q47388420

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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Propofol is an allosteric agon ...... meric ternary GABAA receptors.

@en

Propofol is an allosteric agon ...... meric ternary GABAA receptors.

@nl

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Item

label

Propofol is an allosteric agon ...... meric ternary GABAA receptors.

@en

Propofol is an allosteric agon ...... meric ternary GABAA receptors.

@nl

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Propofol is an allosteric agon ...... meric ternary GABAA receptors.

@en

Propofol is an allosteric agon ...... meric ternary GABAA receptors.

@nl

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Propofol is an allosteric agon ...... meric ternary GABAA receptors.

@en

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Alexander D Johnson

http://www.w3.org/2001/XMLSchema#string

Allison L Germann

http://www.w3.org/2001/XMLSchema#string

Daniel J Shin

http://www.w3.org/2001/XMLSchema#string

Gustav Akk

http://www.w3.org/2001/XMLSchema#string

Joseph H Steinbach

http://www.w3.org/2001/XMLSchema#string

Stuart A Forman

http://www.w3.org/2001/XMLSchema#string

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor

Methionine 286 in transmembrane domain 3 of the GABAA receptor beta subunit controls a binding cavity for propofol and other alkylphenol general anesthetics

Correction for Inhibition Leads to an Allosteric Co-Agonist Model for Pentobarbital Modulation and Activation of α1β3γ2L GABAA Receptors

Tryptophan scanning mutagenesis in TM4 of the GABA(A) receptor alpha1 subunit: implications for modulation by inhaled anesthetics and ion channel structure.

Allosteric activation mechanism of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid type A receptor revealed by mutation of the conserved M2 leucine.

On the application of "a plausible model" of allosteric proteins to the receptor for acetylcholine.

Multiple propofol-binding sites in a γ-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog.

A propofol binding site on mammalian GABAA receptors identified by photolabeling

Multiple Non-Equivalent Interfaces Mediate Direct Activation of GABAA Receptors by Propofol.

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scholarly article

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10.1124/MOL.117.110403

http://www.w3.org/2001/XMLSchema#string

P577

2017-11-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29192122

http://www.w3.org/2001/XMLSchema#string

P921

propofol

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5772375

http://www.w3.org/2001/XMLSchema#string

Propofol is an allosteric agonist with multiple binding sites on concatemeric ternary GABAA receptors.

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P2860

P2860

Propofol is an allosteric agonist with multiple binding sites on concatemeric ternary GABAA receptors.

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P1476

P2093

P2860

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P577

P698

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P356

P1433

P1476

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P356

P577

P698

P921

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