about
The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cellsTET1 and hydroxymethylcytosine in transcription and DNA methylation fidelityRSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.A screen identifies the oncogenic micro-RNA miR-378a-5p as a negative regulator of oncogene-induced senescence.The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner.Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis.Jarid1b targets genes regulating development and is involved in neural differentiationSWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia MaintenanceAn interactive environment for agile analysis and visualization of ChIP-sequencing data.JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity.Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early developmentJmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.The demethylase JMJD2C localizes to H3K4me3-positive transcription start sites and is dispensable for embryonic development.EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas.Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control.Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation.UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1.The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors.The chloride channel inhibitor NS3736 [corrected] prevents bone resorption in ovariectomized rats without changing bone formation.Gene silencing triggers polycomb repressive complex 2 recruitment to CpG islands genome wide.Allele-Specific DNA Methylation Detection by Pyrosequencing®.PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells
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description
hulumtues
@sq
onderzoeker
@nl
researcher
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հետազոտող
@hy
name
Jens V. Johansen
@ast
Jens V. Johansen
@en
Jens V. Johansen
@es
Jens V. Johansen
@nl
Jens V. Johansen
@sl
type
label
Jens V. Johansen
@ast
Jens V. Johansen
@en
Jens V. Johansen
@es
Jens V. Johansen
@nl
Jens V. Johansen
@sl
prefLabel
Jens V. Johansen
@ast
Jens V. Johansen
@en
Jens V. Johansen
@es
Jens V. Johansen
@nl
Jens V. Johansen
@sl
P106
P1153
57193451076
P21
P31
P496
0000-0001-7094-6801