A Quantitative Three-Dimensional Image Analysis Tool for Maximal Acquisition of Spatial Heterogeneity Data.A Personalized Framework for Dynamic Modeling of Disease Trajectories in Chronic Lymphocytic Leukemia.Towards unravelling the kinetics of an acute myeloid leukaemia model system under oxidative and starvation stress: a comparison between two- and three-dimensional cultures.A mathematical model of subpopulation kinetics for the deconvolution of leukaemia heterogeneity.Maximizing neotissue growth kinetics in a perfusion bioreactor: An in silico strategy using model reduction and Bayesian optimization.A systematic framework for the design, simulation and optimization of personalized healthcare: Making and healing bloodPiecewise parametric structure in the pooling problem: from sparse strongly-polynomial solutions to NP-hardness.Bayesian Multi-Objective Optimisation with Mixed Analytical and Black-Box Functions: Application to Tissue EngineeringGlobal optimization advances in Mixed-Integer Nonlinear Programming, MINLP, and Constrained Derivative-Free Optimization, CDFODynamically generated cutting planes for mixed-integer quadratically constrained quadratic programs and their incorporation into GloMIQO 2ANTIGONE: Algorithms for coNTinuous / Integer Global Optimization of Nonlinear EquationsA Framework for Globally Optimizing Mixed-Integer Signomial ProgramsGloMIQO: Global mixed-integer quadratic optimizerGlobal optimization of mixed-integer quadratically-constrained quadratic programs (MIQCQP) through piecewise-linear and edge-concave relaxationsGlobal optimization of a MINLP process synthesis model for thermochemical based conversion of hybrid coal, biomass, and natural gas to liquid fuelsA generalization of classical αBB underestimation to include bilinear termsContinuous-time modeling and global optimization approach for scheduling of crude oil operationsScheduling of crude oil operations under demand uncertainty: A robust optimization framework coupled with global optimizationAPOGEE: Global optimization of standard, generalized, and extended pooling problems via linear and logarithmic partitioning schemesMathematical modeling and global optimization of large-scale extended pooling problems with the (EPA) complex emissions constraintsGlobal Optimization of Large-Scale Generalized Pooling Problems: Quadratically Constrained MINLP ModelsGlobal Optimization and Parametric Analysis of Large-Scale Extended Pooling ProblemsGlobal Optimization of Gas Lifting Operations: A Comparative Study of Piecewise Linear FormulationsComputational Comparison of Piecewise−Linear Relaxations for Pooling ProblemsStem cell biomanufacturing under uncertainty: A case study in optimizing red blood cell production.
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American computer scientist and academic
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