about
Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarizationIdentification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomainsVPS33B regulates protein sorting into and maturation of α-granule progenitor organelles in mouse megakaryocytesThe tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosisTissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivoSyk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells.Platelet actin nodules are podosome-like structures dependent on Wiskott-Aldrich syndrome protein and ARP2/3 complex.Studies on the actin-binding protein HS1 in platelets.Critical role of Src-Syk-PLC{gamma}2 signaling in megakaryocyte migration and thrombopoiesis.Cytoskeletal regulation of platelet formation: Coordination of F-actin and microtubules.CLEC-2-dependent activation of mouse platelets is weakly inhibited by cAMP but not by cGMPSelf-incompatibility triggers programmed cell death in Papaver pollen.Podosomes in adhesion, migration, mechanosensing and matrix remodeling.Investigating mechanisms involved in the self-incompatibility response in Papaver rhoeas.Tuba and N-WASP function cooperatively to position the central lumen during epithelial cyst morphogenesispH-controlled delivery of luminescent europium coated nanoparticles into platelets.Actin depolymerization is sufficient to induce programmed cell death in self-incompatible pollen.The actin binding proteins cortactin and HS1 are dispensable for platelet actin nodule and megakaryocyte podosome formation.CRISPR-Cas9 Mediated Labelling Allows for Single Molecule Imaging and Resolution.Prostacyclin reverses platelet stress fibre formation causing platelet aggregate instability.Accessible Synthetic Probes for Staining Actin inside Platelets and Megakaryocytes by Employing Lifeact Peptide.Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect.Reversal of stress fibre formation by Nitric Oxide mediated RhoA inhibition leads to reduction in the height of preformed thrombi.Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets.Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membraneOptimised CRISPR-Cas9 mediated single molecule imaging for accurate quantification through endogenous expressionFormin proteins in megakaryocytes and platelets: regulation of actin and microtubule dynamicsG-protein coupled and ITAM receptor regulation of the formin FHOD1 through Rho Kinase in plateletsIdentification of a novel, actin-rich structure, the actin nodule, in the early stages of platelet spreadingOptimised insert design for improved single-molecule imaging and quantification through CRISPR-Cas9 mediated knock-inTopological data analysis quantifies biological nano-structure from single molecule localization microscopySMIFH2 inhibition of platelets demonstrates a critical role for formin proteins in platelet cytoskeletal dynamicsHigh-throughput platelet spreading analysis: a tool for the diagnosis of platelet-based bleeding disordersAn adaptable analysis workflow for characterization of platelet spreading and morphologySeeing is believing: use of advanced imaging to study platelets and megakaryocytes
P50
Q24301355-589D2FB3-EFAC-4449-90B8-B97F64B51DD6Q24313296-64C254A4-325A-471A-993C-8CD7FDF6BF8CQ28504778-465E6BE0-C568-46D7-98D0-50A9ADCF2DB6Q28509969-CF7967F9-F432-484E-9A40-CB0A6C02A193Q30572348-32D1A186-BACA-4A96-9B51-0AF95C8E03EDQ30611441-95E66F6B-339C-4EDD-9C99-0DFC5C9E6BC4Q30653580-6460966C-1C90-45C6-BEE4-73F7B21D85F8Q30837279-1F468435-EE61-49A1-997F-3B6A2747A30BQ33389501-C58C59EB-B2F1-436E-905B-C68FC66E99A1Q33424742-59720560-FBB5-4712-BCB5-09328E2D0DFBQ34069541-063DE94D-3319-4852-9F22-B61187ED4EBCQ34321855-C2579BB2-71AD-42C3-A2E1-2E90388FF97DQ34785129-20169FD0-7E16-4692-84A9-CB636C12276AQ35213558-ADE24BF4-81B6-4513-8745-40FE86D12A1DQ35534085-8B3A6457-19E1-4CC9-B57E-E9E0024E83C6Q35750866-1DC7E304-1D7E-4DBA-9822-5E640A8194A7Q36118250-64E1F963-9645-4C5F-873A-4A52A6D163CFQ37611165-1D30CAE3-0041-4840-89FD-B7E510FCEE69Q38641451-08F570EB-526D-41A8-877B-BC8F71AF8740Q38674731-82FCD16C-A368-4734-8857-66FDF7CD7D4DQ40848535-46F6D8AE-0662-4DE5-9C8E-D0BCCC1DEF84Q47363826-A59CB185-420C-4E3F-BF0E-505412E3F29CQ50324626-CB942062-7136-4A41-8A84-559B6E8B0657Q51088958-0B3BC258-386C-4711-878D-DC08B0C1D577Q59122962-F5E390BD-62D3-4A99-92C9-AAB2F0D11559Q60482381-CA3B1C8A-F798-42A7-A5F1-91C0CE8FCD8FQ62014471-218A5E9B-1E23-4E80-B4FA-449FE7F173C1Q62014598-10BCD726-EAA1-413E-BFA1-F929D5CF4D4DQ62014624-B13241CF-84F9-4770-BDFC-62124718B8E6Q90441455-19A50A29-1D19-40ED-8FA0-F73F511696F6Q90794215-9D6DD353-BC67-46CB-8814-7F5640480BB5Q92598838-5F65F19E-BC4F-42D7-9790-867035900FC2Q92916860-9BE196E4-74F7-42CC-B8FB-9C7E425A5C86Q93159166-E2B47CFB-086C-4C25-9F38-0D57E05162CEQ95295350-48B41ED4-F12C-4EEC-BDC2-BA985B1369FD
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Steven G. Thomas
@ast
Steven G. Thomas
@en
Steven G. Thomas
@es
Steven G. Thomas
@nl
Steven G. Thomas
@sl
type
label
Steven G. Thomas
@ast
Steven G. Thomas
@en
Steven G. Thomas
@es
Steven G. Thomas
@nl
Steven G. Thomas
@sl
prefLabel
Steven G. Thomas
@ast
Steven G. Thomas
@en
Steven G. Thomas
@es
Steven G. Thomas
@nl
Steven G. Thomas
@sl
P106
P1153
7404655444
P21
P31
P496
0000-0001-8733-7842