about
State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiologyTime-resolved and two-photon emission imaging microscopy of live cells with inert platinum complexesImmunocompetent 3D model of human upper airway for disease modeling and in vitro drug evaluation.Direct laser writing of 3D scaffolds for neural tissue engineering applications.A selective small molecule agonist of the melanocortin-1 receptor inhibits lipopolysaccharide-induced cytokine accumulation and leukocyte infiltration in mice.Laser exposure of gold nanorods can induce intracellular calcium transients.Nerve guides manufactured from photocurable polymers to aid peripheral nerve repair.alpha-Melanocyte stimulating hormone, inflammation and human melanoma.Melanocortin signalling mechanisms.Next generation nerve guides: materials, fabrication, growth factors, and cell delivery.Investigating NF-κB signaling in lung fibroblasts in 2D and 3D culture systems.Photochemically modified diamond-like carbon surfaces for neural interfaces.Mechanisms of fluid-flow-induced matrix production in bone tissue engineering.An aligned 3D neuronal-glial co-culture model for peripheral nerve studies.Development of a bioreactor for evaluating novel nerve conduits.Investigation of fibroblast and keratinocyte cell-scaffold interactions using a novel 3D cell culture system.Culture of skin cells in 3D rather than 2D improves their ability to survive exposure to cytotoxic agents.Melanocyte stimulating hormone peptides inhibit TNF-alpha signaling in human dermal fibroblast cells.Immobilized alpha-melanocyte stimulating hormone 10-13 (GKPV) inhibits tumor necrosis factor-alpha stimulated NF-kappaB activity.Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function.The participation of proliferative keratinocytes in the preimmune response to sensitizing agents.Skin stem cell hypotheses and long term clone survival--explored using agent-based modellingOxygen Mapping of Melanoma Spheroids using Small Molecule Platinum Probe and Phosphorescence Lifetime Imaging Microscopy.An anatomical study of porcine peripheral nerve and its potential use in nerve tissue engineering.Differential effects of glutathione S-transferase pi (GSTP1) haplotypes on cell proliferation and apoptosis.Development of a 3D human in vitro skin co-culture model for detecting irritants in real-time.Dinuclear ruthenium(II) complexes as two-photon, time-resolved emission microscopy probes for cellular DNA.Melanoma cell attachment, invasion, and integrin expression is upregulated by tumor necrosis factor alpha and suppressed by alpha melanocyte stimulating hormone.Development of biodegradable electrospun scaffolds for dermal replacement.Anti-microbial action of melanocortin peptides and identification of a novel X-Pro-D/L-Val sequence in Gram-positive and Gram-negative bacteria.Sodium salicylate inhibits TNF-alpha-induced NF-kappaB activation, cell migration, invasion and ICAM-1 expression in human melanoma cells.Tumor necrosis factor alpha increases and alpha-melanocyte-stimulating hormone reduces uveal melanoma invasion through fibronectin.Alpha-MSH inhibits inflammatory signalling in Schwann cells.Arginine-glycine-aspartic acid functional branched semi-interpenetrating hydrogels.Real-time detection of stress in 3D tissue-engineered constructs using NF-kappaB activation in transiently transfected human dermal fibroblast cells.Development of a 3D cell culture system for investigating cell interactions with electrospun fibers.In situ image analysis of interactions between normal human keratinocytes and fibroblasts cultured in three-dimensional fibrin gels.Development of a closed bioreactor system for culture of tissue-engineered skin at an air-liquid interface.Self-organization of skin cells in three-dimensional electrospun polystyrene scaffolds.Developments in xenobiotic-free culture of human keratinocytes for clinical use.
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
John W. Haycock
@ast
John W. Haycock
@en
John W. Haycock
@es
John W. Haycock
@nl
John W. Haycock
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type
label
John W. Haycock
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John W. Haycock
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John W. Haycock
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John W. Haycock
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John W. Haycock
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prefLabel
John W. Haycock
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John W. Haycock
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John W. Haycock
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John W. Haycock
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John W. Haycock
@sl
P106
P1153
35237001100
P21
P31
P496
0000-0002-3950-3583