about
CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroupAge-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington diseaseMice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease.A fully humanized transgenic mouse model of Huntington disease.Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's diseaseCholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes.Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14.Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin.Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation.Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease.Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain.HDBuzz: empowering patients through accessible education.Automated deformation analysis in the YAC128 Huntington disease mouse model.Early Detection of Apathetic Phenotypes in Huntington's Disease Knock-in Mice Using Open Source Tools.Transcriptional regulatory networks underlying gene expression changes in Huntington's disease.
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description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jeffrey B Carroll
@ast
Jeffrey B Carroll
@en
Jeffrey B Carroll
@es
Jeffrey B Carroll
@nl
Jeffrey B Carroll
@sl
type
label
Jeffrey B Carroll
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Jeffrey B Carroll
@en
Jeffrey B Carroll
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Jeffrey B Carroll
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Jeffrey B Carroll
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altLabel
Jeff Carroll
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prefLabel
Jeffrey B Carroll
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Jeffrey B Carroll
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Jeffrey B Carroll
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Jeffrey B Carroll
@nl
Jeffrey B Carroll
@sl
P106
P21
P2798
P31
P496
0000-0003-1711-8868