Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.

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Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.Identification and Characterization of USP7 Targets in Cancer Cells The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel

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P2860

Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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name

Structure-Guided Development o ...... Active-Site Inhibitor of USP7.

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Structure-Guided Development o ...... Active-Site Inhibitor of USP7.

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type

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Structure-Guided Development o ...... Active-Site Inhibitor of USP7.

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Structure-Guided Development o ...... Active-Site Inhibitor of USP7.

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Structure-Guided Development o ...... Active-Site Inhibitor of USP7.

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Structure-Guided Development o ...... Active-Site Inhibitor of USP7.

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P1476

Structure-Guided Development o ...... Active-Site Inhibitor of USP7

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P2093

Deepika Das

http://www.w3.org/2001/XMLSchema#string

Dharminder Chauhan

http://www.w3.org/2001/XMLSchema#string

Ellen L Weisberg

http://www.w3.org/2001/XMLSchema#string

Hyuk-Soo Seo

http://www.w3.org/2001/XMLSchema#string

Ilaria Lamberto

http://www.w3.org/2001/XMLSchema#string

John R Engen

http://www.w3.org/2001/XMLSchema#string

Kenneth C Anderson

http://www.w3.org/2001/XMLSchema#string

Roxana E Iacob

http://www.w3.org/2001/XMLSchema#string

Sara J Buhrlage

http://www.w3.org/2001/XMLSchema#string

Sirano Dhe-Paganon

http://www.w3.org/2001/XMLSchema#string

P2860

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases

A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing

The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

Suppression of cancer cell growth by promoting cyclin D1 degradation

A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolution

Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis

PHENIX: a comprehensive Python-based system for macromolecular structure solution

P304

1490-1500.e11

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scholarly article

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10.1016/J.CHEMBIOL.2017.09.003

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P478

http://www.w3.org/2001/XMLSchema#string

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Nathan J Schauer

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2017-10-19T00:00:00Z

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29056421

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P932

5749250

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Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.

about

P2860

P2860

Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.

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