Human alternative Klotho mRNA is a nonsense-mediated mRNA decay target inefficiently spliced in renal disease.

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FGF23 Actions on Target Tissues-With and Without Klotho.α-Klotho's effects on mineral homeostasis are fibroblast growth factor-23 dependent.Klotho is upregulated in human cardiomyopathy independently of circulating Klotho levels.

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Human alternative Klotho mRNA is a nonsense-mediated mRNA decay target inefficiently spliced in renal disease.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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Human alternative Klotho mRNA ...... ntly spliced in renal disease.

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Human alternative Klotho mRNA ...... ntly spliced in renal disease.

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Human alternative Klotho mRNA ...... ntly spliced in renal disease.

@en

Human alternative Klotho mRNA ...... ntly spliced in renal disease.

@nl

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Human alternative Klotho mRNA ...... ntly spliced in renal disease.

@en

Human alternative Klotho mRNA ...... ntly spliced in renal disease.

@nl

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Human alternative Klotho mRNA ...... ntly spliced in renal disease.

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Arjan Diepstra

http://www.w3.org/2001/XMLSchema#string

Geert Harms

http://www.w3.org/2001/XMLSchema#string

Henri G Leuvenink

http://www.w3.org/2001/XMLSchema#string

Jan-Luuk Hillebrands

http://www.w3.org/2001/XMLSchema#string

Matijs van Meurs

http://www.w3.org/2001/XMLSchema#string

Rik Mencke

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Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein

Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Suppression of aging in mice by the hormone Klotho

Klotho and phosphate are modulators of pathologic uremic cardiac remodeling.

Klotho converts canonical FGF receptor into a specific receptor for FGF23

Augmented Wnt signaling in a mammalian model of accelerated aging

Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein

N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models

Molecular cloning of rat klotho cDNA: markedly decreased expression of klotho by acute inflammatory stress

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scholarly article

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10.1172/JCI.INSIGHT.94375

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Jill Moser

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2017-10-19T00:00:00Z

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29046474

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P932

5846909

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Human alternative Klotho mRNA is a nonsense-mediated mRNA decay target inefficiently spliced in renal disease.

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P2860

P2860

Human alternative Klotho mRNA is a nonsense-mediated mRNA decay target inefficiently spliced in renal disease.

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type

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P1433

P1476

P2093

P2860

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P31

P356

P433

P478

P50

P577

P698

P932