A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury.

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Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases

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A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury.

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A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury.

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A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury.

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A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury.

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A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury.

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A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury.

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A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury.

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P1476

A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury.

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Coleen M Atkins

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Dale A Calixte

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David J Titus

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Mark E Gurney

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Nicole M Wilson

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Oscar Alcazar

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W Dalton Dietrich

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Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety

Oral Apremilast for the Treatment of Plaque Psoriasis

Cyclic AMP-specific phosphodiesterase-4 as a target for the development of antidepressant drugs

Exome sequencing identifies PDE4D mutations as another cause of acrodysostosis

Keynote review: phosphodiesterase-4 as a therapeutic target

A new model of Pde4d deficiency: genetic knock-down of PDE4D enzyme in rats produces an antidepressant phenotype without spatial cognitive effects.

GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses

Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect

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38-49

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scholarly article

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10.1016/J.NLM.2017.12.008

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P478

148

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2017-12-30T00:00:00Z

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29294383

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5844849

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A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury.

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P2860

A negative allosteric modulator of PDE4D enhances learning after traumatic brain injury.

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P1433

P1476

P2093

P2860

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P356

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P356

P1433

P1476

P2093

P2860

P304

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P356

P478

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