Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.

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Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.

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Substitution of Aromatic Resid ...... of New Cyclic Sesquiterpenes.

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Substitution of Aromatic Resid ...... of New Cyclic Sesquiterpenes.

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Substitution of Aromatic Resid ...... of New Cyclic Sesquiterpenes.

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Substitution of Aromatic Resid ...... of New Cyclic Sesquiterpenes.

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Substitution of Aromatic Resid ...... of New Cyclic Sesquiterpenes.

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Substitution of Aromatic Resid ...... of New Cyclic Sesquiterpenes.

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P1476

Substitution of Aromatic Resid ...... n of New Cyclic Sesquiterpenes

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P2093

Golda H Barrow

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Wayne K W Chou

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P2860

Bornyl diphosphate synthase: structure and strategy for carbocation manipulation by a terpenoid cyclase.

MolProbity: all-atom structure validation for macromolecular crystallography

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Processing of X-ray diffraction data collected in oscillation mode

Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis

Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates ,

Structure of 2-Methylisoborneol Synthase from Streptomyces coelicolor and Implications for the Cyclization of a Noncanonical C -Methylated Monoterpenoid Substrate

Mechanistic Insights from the Binding of Substrate and Carbocation Intermediate Analogues to Aristolochene Synthase

1.55Å-resolution structure of ent-copalyl diphosphate synthase and exploration of general acid function by site-directed mutagenesis

Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi -Isozizaene Synthase

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5798-5811

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scholarly article

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10.1021/ACS.BIOCHEM.7B00895

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English

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P478

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2017-10-17T00:00:00Z

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28967743

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5664225

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