PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease.
about
Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1).PepT1 mediates transport of the proinflammatory bacterial tripeptide L-Ala-{gamma}-D-Glu-meso-DAP in intestinal epithelial cells.Nod1 and nod2 are expressed in human and murine renal tubular epithelial cells and participate in renal ischemia reperfusion injury.The peptide transporter PEPT1 is expressed in distal colon in rodents and humans and contributes to water absorption.CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in miceColonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation.Colonic miRNA expression/secretion, regulated by intestinal epithelial PepT1, plays an important role in cell-to-cell communication during colitis.L-Ala-γ-D-Glu-meso-diaminopimelic acid (DAP) interacts directly with leucine-rich region domain of nucleotide-binding oligomerization domain 1, increasing phosphorylation activity of receptor-interacting serine/threonine-protein kinase 2 and its intThe PepT1-NOD2 signaling pathway aggravates induced colitis in miceThe role and pathophysiological relevance of membrane transporter PepT1 in intestinal inflammation and inflammatory bowel disease.Apple juice greatly reduces systemic exposure to atenololProton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications.Identification of Susceptibility Genes of Adult Asthma in French Canadian WomenCritical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model.Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.Impact of intestinal PepT1 on the kinetics and dynamics of N-formyl-methionyl-leucyl-phenylalanine, a bacterially-produced chemotactic peptide.pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signalingDrug transporter pharmacogenetics in nucleoside-based therapies.Epithelial transport in inflammatory bowel diseases.Intestinal barrier dysfunction: implications for chronic inflammatory conditions of the bowel.Di- and tripeptide transport in vertebrates: the contribution of teleost fish models.Clinical relevance of intestinal peptide uptake.PepT1 expressed in immune cells has an important role in promoting the immune response during experimentally induced colitis.Lactobacillus plantarum consumption increases PepT1-mediated amino acid absorption by enhancing protein kinase C activity in spontaneously colitic mice.Association between polymorphisms in and genes and development of obesity in Chinese subjects
P2860
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P2860
PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease.
@en
PepT1 oligopeptide transporter
@nl
type
label
PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease.
@en
PepT1 oligopeptide transporter
@nl
prefLabel
PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease.
@en
PepT1 oligopeptide transporter
@nl
P2093
P2860
P50
P356
P1476
PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease.
@en
P2093
Anna Hellquist
Colin L Noble
Francesca Anedda
Francesca Bresso
Gunnar B Lindgren
Jack Satsangi
Kimmo Kontula
Leena Halme
Leif Torkvist
Maarit Lappalainen
P2860
P304
P356
10.1002/IBD.20963
P577
2009-10-01T00:00:00Z