RAF inhibition overcomes resistance to TRAIL-induced apoptosis in melanoma cells.
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PI3K/AKT Signaling Pathway Is Essential for Survival of Induced Pluripotent Stem CellsSynergistic anti-tumor activity and inhibition of angiogenesis by cotargeting of oncogenic and death receptor pathways in human melanomahvTRA, a novel TRAIL receptor agonist, induces apoptosis and sustained growth retardation in melanoma.Blocks to thyroid cancer cell apoptosis can be overcome by inhibition of the MAPK and PI3K/AKT pathways.Towards combinatorial targeted therapy in melanoma: from pre-clinical evidence to clinical application (review).Inhibition of B-Raf/MEK/ERK signaling suppresses DR5 expression and impairs response of cancer cells to DR5-mediated apoptosis and T cell-induced killing.Silencing the KCNK9 potassium channel (TASK-3) gene disturbs mitochondrial function, causes mitochondrial depolarization, and induces apoptosis of human melanoma cells.Melanoma never says die.Critical role of reactive oxygen species (ROS) for synergistic enhancement of apoptosis by vemurafenib and the potassium channel inhibitor TRAM-34 in melanoma cells.Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma.Reduced risk of apoptosis: mechanisms of stress responses.Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy.BH3-only proteins: possible proapoptotic triggers for melanoma therapy.Blockage of the mevalonate pathway overcomes the apoptotic resistance to MEK inhibitors with suppressing the activation of Akt in cancer cells.
P2860
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P2860
RAF inhibition overcomes resistance to TRAIL-induced apoptosis in melanoma cells.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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name
RAF inhibition overcomes resistance to TRAIL-induced apoptosis in melanoma cells.
@en
RAF inhibition overcomes resistance to TRAIL-induced apoptosis in melanoma cells.
@nl
type
label
RAF inhibition overcomes resistance to TRAIL-induced apoptosis in melanoma cells.
@en
RAF inhibition overcomes resistance to TRAIL-induced apoptosis in melanoma cells.
@nl
prefLabel
RAF inhibition overcomes resistance to TRAIL-induced apoptosis in melanoma cells.
@en
RAF inhibition overcomes resistance to TRAIL-induced apoptosis in melanoma cells.
@nl
P2093
P356
P1476
RAF inhibition overcomes resistance to TRAIL-induced apoptosis in melanoma cells.
@en
P2093
Anja Berger
Jürgen Eberle
Michael Plötz
Nicholas-Frederik Kuhn
Sandra-Annika Quast
Uwe Trefzer
P2888
P304
P356
10.1038/JID.2013.347
P407
P577
2013-08-16T00:00:00Z