Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease.
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Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrum.CEACAM6 gene variants in inflammatory bowel diseaseEffect of hookworm infection on wheat challenge in celiac disease--a randomised double-blinded placebo controlled trialThe 4q27 locus and prostate cancer risk.The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease.PPAR signaling pathway and cancer-related proteins are involved in celiac disease-associated tissue damage.Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significanceGlucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients.Th17-related cytokines: new players in the control of chronic intestinal inflammationThe role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's diseaseTh17-related genes and celiac disease susceptibility.PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease backgroundAnalysis of IL12B gene variants in inflammatory bowel disease.The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067.Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease.IRGM variants and susceptibility to inflammatory bowel disease in the German population.IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H)Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21The Impact of PPARγ Genetic Variants on IBD Susceptibility and IBD Disease Course.Generation and characterization of human anti-human IL-21 neutralizing monoclonal antibodiesThe Correlation of Serum IL-12B Expression With Disease Activity in Patients With Inflammatory Bowel DiseaseGenome-wide association studies--a summary for the clinical gastroenterologist.NF-κB Activation in T Helper 17 Cell Differentiation.The IL-23/IL-17 pathway in inflammatory bowel disease.The role of tumour necrosis factor in the pathogenesis of immune-mediated diseases.Hedgehog is an anti-inflammatory epithelial signal for the intestinal lamina propria.Association of UBASH3A gene polymorphism and atopic dermatitis in the Chinese Han population.Autoimmune diseases association study with the KIAA1109-IL2-IL21 region in a Tunisian population.Celiac disease in a child with ulcerative colitis: a possible genetic association.Common and different genetic background for rheumatoid arthritis and coeliac disease.Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis.Nutrigenomics and inflammatory bowel diseases.Genome-wide association study to identify variants associated with acute severe vaso-occlusive pain in sickle cell anemia.Investigation of JAK2, STAT3 and CCR6 polymorphisms and their gene-gene interactions in inflammatory bowel disease.Intestinal neuroendocrine cells and goblet cells are mediators of IL-17A-amplified epithelial IL-17C production in human inflammatory bowel disease.Consolidation of Evidence for Association of the KIAA1109-TENR-IL2-IL21 rs6822844 Variant With Crohn's Disease
P2860
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P2860
Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Novel genetic risk markers for ...... ve colitis and celiac disease.
@en
Novel genetic risk markers for ...... ve colitis and celiac disease.
@nl
type
label
Novel genetic risk markers for ...... ve colitis and celiac disease.
@en
Novel genetic risk markers for ...... ve colitis and celiac disease.
@nl
prefLabel
Novel genetic risk markers for ...... ve colitis and celiac disease.
@en
Novel genetic risk markers for ...... ve colitis and celiac disease.
@nl
P2093
P2860
P356
P1476
Novel genetic risk markers for ...... ve colitis and celiac disease.
@en
P2093
Burkhard Göke
Johannes Stallhofer
Jürgen Glas
Martin Lacher
Martin Wetzke
Matthias Folwaczny
Peter Lohse
Sibylle Koletzko
Simone Pfennig
Stephan Brand
P2860
P2888
P304
P356
10.1038/AJG.2009.163
P407
P577
2009-05-19T00:00:00Z
P6179
1049684585