Convergence of Wnt signaling on the HNF4alpha-driven transcription in controlling liver zonation.
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Role and regulation of β-catenin signaling during physiological liver growthVascular patterning sets the stage for macro and micro hepatic architectureCrosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipidsβ-Catenin Signaling and Roles in Liver Homeostasis, Injury, and TumorigenesisSubcellular and cellular locations of nitric oxide synthase isoforms as determinants of health and diseaseEvidence for a common progenitor of epithelial and mesenchymal components of the liver.SILAC labeling coupled to shotgun proteomics analysis of membrane proteins of liver stem/hepatocyte allows to candidate the inhibition of TGF-beta pathway as causal to differentiation.Liver zonation: Novel aspects of its regulation and its impact on homeostasis.Liver tissue engineering in the evaluation of drug safety.Beta-catenin signaling in hepatic development and progenitors: which way does the WNT blow?PATHOME: an algorithm for accurately detecting differentially expressed subpathways.Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad.An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesisThe Wnt/β-catenin signaling pathway in liver biology and disease.Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.Calpain induces N-terminal truncation of β-catenin in normal murine liver development: diagnostic implications in hepatoblastomas.Nuclear receptor CAR specifically activates the two-pore K+ channel Kcnk1 gene in male mouse livers, which attenuates phenobarbital-induced hepatic hyperplasia.Sexually Dimorphic Expression of eGFP Transgene in the Akr1A1 Locus of Mouse Liver Regulated by Sex Hormone-Related Epigenetic Remodeling.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Unbalanced distribution of materials: the art of giving rise to hepatocytes from liver stem/progenitor cells.The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition.Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver diseaseComputational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion.Wnt signalling and the control of cellular metabolism.Cellular and molecular basis of liver development.Hepatic progenitors for liver disease: current positionMolecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte.Conversion of one cell type into another: implications for understanding organ development, pathogenesis of cancer and generating cells for therapy.Regulation of hepatocyte identity and quiescence.Anti-cancer effect of N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2,3-dihydronaphtho[1,2-b]furan-2-carboxamide, a novel synthetic compound.Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer.Metabolic zonation of the liver: The oxygen gradient revisited.Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems.Pericentral activity of alpha-fetoprotein enhancer 3 and glutamine synthetase upstream enhancer in the adult liver are regulated by β-catenin in mice.The stable repression of mesenchymal program is required for hepatocyte identity: a novel role for hepatocyte nuclear factor 4α.Safety, Tolerability, and Preliminary Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/β-Catenin Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center, Open-Label, Dose Escalation Phase 1 Trial.A pre-neoplastic epigenetic field defect in HCV-infected liver at transcription factor binding sites and polycomb targets.An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs.Coordinate regulation of cytochrome P450 1a1 expression in mouse liver by the aryl hydrocarbon receptor and the beta-catenin pathway.Deciphering liver zonation: new insights into the β-catenin, Tcf4, and HNF4α triad.
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Convergence of Wnt signaling on the HNF4alpha-driven transcription in controlling liver zonation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Convergence of Wnt signaling o ...... in controlling liver zonation.
@en
Convergence of Wnt signaling o ...... in controlling liver zonation.
@nl
type
label
Convergence of Wnt signaling o ...... in controlling liver zonation.
@en
Convergence of Wnt signaling o ...... in controlling liver zonation.
@nl
prefLabel
Convergence of Wnt signaling o ...... in controlling liver zonation.
@en
Convergence of Wnt signaling o ...... in controlling liver zonation.
@nl
P50
P1433
P1476
Convergence of Wnt signaling o ...... in controlling liver zonation.
@en
P2093
Laura Santangelo
Tonino Alonzi
P304
P356
10.1053/J.GASTRO.2009.05.038
P407
P577
2009-05-18T00:00:00Z