DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update.

about

DPYD genotype-guided fluoropyrimidines dose: is it ready for prime time?Exploring the Use of Molecular Biomarkers for Precision Medicine in Age-Related Macular Degeneration.SNPs in predicting clinical efficacy and toxicity of chemotherapy: walking through the quicksand.

P2860

Q50089496-A3145A57-63F3-48EC-90CA-498C70F1D0F3 Q52559837-2F56E1A3-9F25-40A7-A944-CA0DBE04CDAC Q55497899-BCD63597-C739-4396-88B9-84CE561BB6C4

P2860

DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update.

Item

http://www.wikidata.org/entity/Q47768032

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh

2017年學術文章

@zh-hant

name

DPYD genotype-guided dose indi ...... call for a drug label update.

@en

DPYD genotype-guided dose indi ...... call for a drug label update.

@nl

type

Item

label

DPYD genotype-guided dose indi ...... call for a drug label update.

@en

DPYD genotype-guided dose indi ...... call for a drug label update.

@nl

prefLabel

DPYD genotype-guided dose indi ...... call for a drug label update.

@en

DPYD genotype-guided dose indi ...... call for a drug label update.

@nl

P1476

DPYD genotype-guided dose indi ...... call for a drug label update.

@en

P2093

A Cats

http://www.w3.org/2001/XMLSchema#string

F L Opdam

http://www.w3.org/2001/XMLSchema#string

J H Beijnen

http://www.w3.org/2001/XMLSchema#string

J H M Schellens

http://www.w3.org/2001/XMLSchema#string

L M Henricks

http://www.w3.org/2001/XMLSchema#string

P2860

5-fluorouracil: mechanisms of action and clinical strategies

A point mutation in an invariant splice donor site leads to exon skipping in two unrelated Dutch patients with dihydropyrimidine dehydrogenase deficiency

A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS

Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data.

Dihydropyrimidine dehydrogenase deficiency and fluorouracil-related toxicity.

Comparative functional analysis of DPYD variants of potential clinical relevance to dihydropyrimidine dehydrogenase activity

DPD-based adaptive dosing of 5-FU in patients with head and neck cancer: impact on treatment efficacy and toxicity.

Intragenic deletions and a deep intronic mutation affecting pre-mRNA splicing in the dihydropyrimidine dehydrogenase gene as novel mechanisms causing 5-fluorouracil toxicity.

Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity.

Clinical Pharmacogenetics Implementation Consortium guidelines for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing

P304

2915-2922

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/ANNONC/MDX411

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2017-08-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29045513

http://www.w3.org/2001/XMLSchema#string

DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update.

about

P2860

P2860

DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698