A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse.
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Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determinationFailure of SOX9 regulation in 46XY disorders of sex development with SRY, SOX9 and SF1 mutationsSOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epitheliumThe mouse juvenile spermatogonial depletion (jsd) phenotype is due to a mutation in the X-derived retrogene, mUtp14bMale sex determination: insights into molecular mechanismsControl of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factorsMolecular players involved in temperature-dependent sex determination and sex differentiation in Teleost fishRapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryosMammalian sex determination—insights from humans and mice.The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiationTestis development requires the repression of Wnt4 by Fgf signalingGenetic control of testis developmentAnalyzing the coordinated gene network underlying temperature-dependent sex determination in reptilesDeletion of the Parkin coregulated gene causes male sterility in the quaking(viable) mouse mutantA transgenic insertion on mouse chromosome 17 inactivates a novel immunoglobulin superfamily gene potentially involved in sperm-egg fusionInsulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in miceMouse model systems to study sex chromosome genes and behavior: relevance to humans.Epithelial-mesenchymal crosstalk in Wolffian duct and fetal testis cord development.Conserved noncoding elements follow power-law-like distributions in several genomes as a result of genome dynamics.Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system.R-spondin1 and FOXL2 act into two distinct cellular types during goat ovarian differentiation.The cerebellin 4 precursor gene is a direct target of SRY and SOX9 in miceRole of Sox-9, ER81 and VE-cadherin in retinoic acid-mediated trans-differentiation of breast cancer cellsStructural relationships between highly conserved elements and genes in vertebrate genomes.A genomic atlas of human adrenal and gonad development.Global survey of protein expression during gonadal sex determination in miceOestrogen blocks the nuclear entry of SOX9 in the developing gonad of a marsupial mammalTemperature, genes, and sex: a comparative view of sex determination in Trachemys scripta and Mus musculusEx vivo magnetofection: a novel strategy for the study of gene function in mouse organogenesis.The road to maleness: from testis to Wolffian duct.Copy number variation in patients with disorders of sex development due to 46,XY gonadal dysgenesis.In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures.Regulation of sex determination in mice by a non-coding genomic region.Determination and stability of gonadal sexLong-range control of gene expression: emerging mechanisms and disruption in disease.Position effects due to chromosome breakpoints that map approximately 900 Kb upstream and approximately 1.3 Mb downstream of SOX9 in two patients with campomelic dysplasia.Fine mapping of chromosome 17 translocation breakpoints > or = 900 Kb upstream of SOX9 in acampomelic campomelic dysplasia and a mild, familial skeletal dysplasiaA nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determinationEstablishing sexual dimorphism: conservation amidst diversity?Transient development of ovotestes in XX Sox9 transgenic mice.
P2860
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P2860
A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
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2000年学术文章
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2000年學術文章
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name
A transgenic insertion upstrea ...... XX sex reversal in the mouse.
@en
A transgenic insertion upstrea ...... XX sex reversal in the mouse.
@nl
type
label
A transgenic insertion upstrea ...... XX sex reversal in the mouse.
@en
A transgenic insertion upstrea ...... XX sex reversal in the mouse.
@nl
prefLabel
A transgenic insertion upstrea ...... XX sex reversal in the mouse.
@en
A transgenic insertion upstrea ...... XX sex reversal in the mouse.
@nl
P2093
P356
P1433
P1476
A transgenic insertion upstrea ...... XX sex reversal in the mouse.
@en
P2093
Agoulnik AI
Agoulnik IU
Behringer RR
Harrison WR
Whitworth DJ
P2888
P304
P356
10.1038/82652
P407
P577
2000-12-01T00:00:00Z