Rational design and structure-activity relationship studies of quercetin-amino acid hybrids targeting the anti-apoptotic protein Bcl-xL.

about

Amplifying and broadening the cytotoxic profile of quercetin in cancer cell lines through bioconjugation.On the design principles of peptide-drug conjugates for targeted drug delivery to the malignant tumor site.

P2860

Q48220116-C926C44C-96A2-4223-98BC-011C4436E363 Q55054276-FF3D9691-3AB5-4862-8B04-5210F124BC23

P2860

Rational design and structure-activity relationship studies of quercetin-amino acid hybrids targeting the anti-apoptotic protein Bcl-xL.

Item

http://www.wikidata.org/entity/Q47810232

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

Rational design and structure- ...... anti-apoptotic protein Bcl-xL.

@en

Rational design and structure- ...... anti-apoptotic protein Bcl-xL.

@nl

type

Item

label

Rational design and structure- ...... anti-apoptotic protein Bcl-xL.

@en

Rational design and structure- ...... anti-apoptotic protein Bcl-xL.

@nl

prefLabel

Rational design and structure- ...... anti-apoptotic protein Bcl-xL.

@en

Rational design and structure- ...... anti-apoptotic protein Bcl-xL.

@nl

P1476

Rational design and structure- ...... anti-apoptotic protein Bcl-xL

@en

P2093

Andreas G Tzakos

http://www.w3.org/2001/XMLSchema#string

Antonis D Tsiailanis

http://www.w3.org/2001/XMLSchema#string

Eirinaios I Vrettos

http://www.w3.org/2001/XMLSchema#string

Elena G Geromichalou

http://www.w3.org/2001/XMLSchema#string

George D Geromichalos

http://www.w3.org/2001/XMLSchema#string

Min-Sung Lee

http://www.w3.org/2001/XMLSchema#string

Nisar Sayyad

http://www.w3.org/2001/XMLSchema#string

Seung-Wook Chi

http://www.w3.org/2001/XMLSchema#string

P2860

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

The structure of a Bcl-xL/Bim fragment complex: implications for Bim function

Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family

Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands

Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX

Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity

Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based upon a New Scaffold

Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists

Structure-Guided Rational Design of α/β-Peptide Foldamers with High Affinity for BCL-2 Family Prosurvival Proteins

Structure-guided design of a selective BCL-X(L) inhibitor

P304

7956-7976

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1039/C7OB02045G

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Tahsin F. Kellici

Thomas Mavromoustakos

Maria V Chatziathanasiadou

P577

2017-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28902204

http://www.w3.org/2001/XMLSchema#string

P921

protein design

Rational design and structure-activity relationship studies of quercetin-amino acid hybrids targeting the anti-apoptotic protein Bcl-xL.

about

P2860

P2860

Rational design and structure-activity relationship studies of quercetin-amino acid hybrids targeting the anti-apoptotic protein Bcl-xL.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921