Secondary processing of the Plasmodium falciparum merozoite surface protein-1 (MSP1) by a calcium-dependent membrane-bound serine protease: shedding of MSP133 as a noncovalently associated complex with other fragments of the MSP1.
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Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malariaMerozoite surface protein 1 recognition of host glycophorin A mediates malaria parasite invasion of red blood cellsStructure of the C-terminal domains of merozoite surface protein-1 from Plasmodium knowlesi reveals a novel histidine binding siteMultiple Plasmodium falciparum Merozoite Surface Protein 1 Complexes Mediate Merozoite Binding to Human ErythrocytesNovel putative glycosylphosphatidylinositol-anchored micronemal antigen of Plasmodium falciparum that binds to erythrocytesPlasmodium falciparum subtilisin-like protease 2, a merozoite candidate for the merozoite surface protein 1-42 maturaseA Plasmodium α/β-hydrolase modulates the development of invasive stagesThe merozoite surface protein 1 complex is a platform for binding to human erythrocytes by Plasmodium falciparumProtective immune responses to the 42-kilodalton (kDa) region of Plasmodium yoelii merozoite surface protein 1 are induced by the C-terminal 19-kDa region but not by the adjacent 33-kDa region.Genetic linkage of autologous T cell epitopes in a chimeric recombinant construct improves anti-parasite and anti-disease protective effect of a malaria vaccine candidateDeletion of the Plasmodium falciparum merozoite surface protein 7 gene impairs parasite invasion of erythrocytesA subtilisin-like protein in secretory organelles of Plasmodium falciparum merozoitesFunctional characterization of the propeptide of Plasmodium falciparum subtilisin-like protease-1Systematic genetic analysis of the Plasmodium falciparum MSP7-like family reveals differences in protein expression, location, and importance in asexual growth of the blood-stage parasiteMSP-1 malaria pseudopeptide analogs: biological and immunological significance and three-dimensional structure.Plasmodium falciparum merozoite surface protein 1.Safety and reactogenicity of an MSP-1 malaria vaccine candidate: a randomized phase Ib dose-escalation trial in Kenyan children.Phase 1 study of two merozoite surface protein 1 (MSP1(42)) vaccines for Plasmodium falciparum malariaProtection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responsesLineage-specific positive selection at the merozoite surface protein 1 (msp1) locus of Plasmodium vivax and related simian malaria parasites.The clinical-grade 42-kilodalton fragment of merozoite surface protein 1 of Plasmodium falciparum strain FVO expressed in Escherichia coli protects Aotus nancymai against challenge with homologous erythrocytic-stage parasites.The malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony.Levels of antibody to conserved parts of Plasmodium falciparum merozoite surface protein 1 in Ghanaian children are not associated with protection from clinical malaria.Structural and antigenic properties of merozoite surface protein 4 of Plasmodium falciparum.Vaccine efficacy of recombinant Plasmodium falciparum merozoite surface protein 1 in malaria-naive, -exposed, and/or -rechallenged Aotus vociferans monkeys.Linkage of exogenous T-cell epitopes to the 19-kilodalton region of Plasmodium yoelii merozoite surface protein 1 (MSP1(19)) can enhance protective immunity against malaria and modulate the immunoglobulin subclass response to MSP1(19).Plasmodium falciparum homologue of the genes for Plasmodium vivax and Plasmodium yoelii adhesive proteins, which is transcribed but not translated.Quantifying the importance of MSP1-19 as a target of growth-inhibitory and protective antibodies against Plasmodium falciparum in humans.The human immune response to Plasmodium falciparum includes both antibodies that inhibit merozoite surface protein 1 secondary processing and blocking antibodiesVariation in the expression of a Plasmodium falciparum protein family implicated in erythrocyte invasionAdvances and challenges in malaria vaccine development.Marked variation in MSP-119 antibody responses to malaria in western Kenyan highlands.Analysis of antibodies directed against merozoite surface protein 1 of the human malaria parasite Plasmodium falciparum.Limited polymorphism of the Plasmodium vivax merozoite surface protein 1 gene in isolates from TurkeyRegulated maturation of malaria merozoite surface protein-1 is essential for parasite growth.Molecular interactions between Anopheles stephensi midgut cells and Plasmodium berghei: the time bomb theory of ookinete invasion of mosquitoes.Immunity to asexual blood stage malaria and vaccine approaches.Immunity to recombinant plasmodium falciparum merozoite surface protein 1 (MSP1): protection in Aotus nancymai monkeys strongly correlates with anti-MSP1 antibody titer and in vitro parasite-inhibitory activity.Serum antibodies from malaria-exposed people recognize conserved epitopes formed by the two epidermal growth factor motifs of MSP1(19), the carboxy-terminal fragment of the major merozoite surface protein of Plasmodium falciparumMembers of the merozoite surface protein 7 family with similar expression patterns differ in ability to protect against Plasmodium yoelii malaria.
P2860
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P2860
Secondary processing of the Plasmodium falciparum merozoite surface protein-1 (MSP1) by a calcium-dependent membrane-bound serine protease: shedding of MSP133 as a noncovalently associated complex with other fragments of the MSP1.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
Secondary processing of the Pl ...... h other fragments of the MSP1.
@en
Secondary processing of the Plasmodium falciparum merozoite surface protein-1
@nl
type
label
Secondary processing of the Pl ...... h other fragments of the MSP1.
@en
Secondary processing of the Plasmodium falciparum merozoite surface protein-1
@nl
prefLabel
Secondary processing of the Pl ...... h other fragments of the MSP1.
@en
Secondary processing of the Plasmodium falciparum merozoite surface protein-1
@nl
P1476
Secondary processing of the Pl ...... h other fragments of the MSP1.
@en
P2093
M J Blackman
P304
P356
10.1016/0166-6851(92)90228-C
P577
1992-02-01T00:00:00Z