The PDE4 inhibitor CHF-6001 and LAMAs inhibit bronchoconstriction-induced remodeling in lung slices.

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The PDE4 inhibitor CHF-6001 and LAMAs inhibit bronchoconstriction-induced remodeling in lung slices.

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2017 nî lūn-bûn

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name

The PDE4 inhibitor CHF-6001 an ...... ced remodeling in lung slices.

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The PDE4 inhibitor CHF-6001 an ...... ced remodeling in lung slices.

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label

The PDE4 inhibitor CHF-6001 an ...... ced remodeling in lung slices.

@en

The PDE4 inhibitor CHF-6001 an ...... ced remodeling in lung slices.

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The PDE4 inhibitor CHF-6001 an ...... ced remodeling in lung slices.

@en

The PDE4 inhibitor CHF-6001 an ...... ced remodeling in lung slices.

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P1476

The PDE4 inhibitor CHF-6001 an ...... ced remodeling in lung slices.

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Fabrizio Facchinetti

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Gino Villetti

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Hoeke A Baarsma

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I Sophie T Bos

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Loes E M Kistemaker

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Martina Schmidt

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Maurizio Civelli

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Reinoud Gosens

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Tjitske A Oenema

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P2860

The pathology of chronic obstructive pulmonary disease.

Bronchoconstriction Induces TGF-β Release and Airway Remodelling in Guinea Pig Lung Slices.

Clinical relevance of airway remodelling in airway diseases.

The preclinical pharmacology of roflumilast--a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease.

Selective PDE inhibitors as novel treatments for respiratory diseases.

Distinct PKA and Epac compartmentalization in airway function and plasticity.

Acetylcholine beyond bronchoconstriction: roles in inflammation and remodeling.

Bronchoconstriction and airway biology: potential impact and therapeutic opportunities.

CHF6001 I: a novel highly potent and selective phosphodiesterase 4 inhibitor with robust anti-inflammatory activity and suitable for topical pulmonary administration.

An Official American Thoracic Society Research Statement: Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling.

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L507-L515

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scholarly article

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10.1152/AJPLUNG.00069.2017

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P433

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313

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2017-06-08T00:00:00Z

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28596292

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