Alternative splicing alterations of Ca2+ handling genes are associated with Ca2+ signal dysregulation in myotonic dystrophy type 1 (DM1) and type 2 (DM2) myotubes.
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The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialFunctional KCa1.1 channels are crucial for regulating the proliferation, migration and differentiation of human primary skeletal myoblastsNFAT1 and NFAT3 cooperate with HDAC4 during regulation of alternative splicing of PMCA isoforms in PC12 cellsRestricting calcium currents is required for correct fiber type specification in skeletal muscle.Targeting deregulated AMPK/mTORC1 pathways improves muscle function in myotonic dystrophy type I.How and why are calcium currents curtailed in the skeletal muscle voltage-gated calcium channels?Dysregulation of calcium homeostasis in muscular dystrophies.Physiological and pharmacological modulation of the embryonic skeletal muscle calcium channel splice variant CaV1.1eExcitation-Contraction Coupling Alterations in Myopathies.Investigation of the molecular mechanisms underlying myotonic dystrophy types 1 and 2 cataracts using microRNA‑target gene networks.Two distinct voltage-sensing domains control voltage sensitivity and kinetics of current activation in CaV1.1 calcium channels.CRISPR/Cas9-Mediated Deletion of CTG Expansions Recovers Normal Phenotype in Myogenic Cells Derived from Myotonic Dystrophy 1 Patients.Reduced gliotransmitter release from astrocytes mediates tau-induced synaptic dysfunction in cultured hippocampal neurons.Misregulation of calcium-handling proteins promotes hyperactivation of calcineurin-NFAT signaling in skeletal muscle of DM1 mice.Diversification of the muscle proteome through alternative splicing.miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models.
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Alternative splicing alterations of Ca2+ handling genes are associated with Ca2+ signal dysregulation in myotonic dystrophy type 1 (DM1) and type 2 (DM2) myotubes.
description
2014 nî lūn-bûn
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2014年の論文
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name
Alternative splicing alteratio ...... M1) and type 2 (DM2) myotubes.
@en
Alternative splicing alteratio ...... n in myotonic dystrophy type 1
@nl
type
label
Alternative splicing alteratio ...... M1) and type 2 (DM2) myotubes.
@en
Alternative splicing alteratio ...... n in myotonic dystrophy type 1
@nl
prefLabel
Alternative splicing alteratio ...... M1) and type 2 (DM2) myotubes.
@en
Alternative splicing alteratio ...... n in myotonic dystrophy type 1
@nl
P2860
P50
P356
P1476
Alternative splicing alteratio ...... M1) and type 2 (DM2) myotubes.
@en
P2093
Anna Modoni
Maria Laura Ester Bianchi
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10.1111/NAN.12076
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P577
2014-06-01T00:00:00Z