Association at LRP gene locus with sporadic late-onset Alzheimer's disease.
about
Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's diseaseGenetic risk factors in Alzheimer's diseaseC-terminal 37 residues of LRP promote the amyloidogenic processing of APP independent of FE65Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.Hunting for disease genes in multi-functional diseases.Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid β-peptide elimination from the brainNew therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy.Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.Modulation of beta-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family.Neurovascular defects and faulty amyloid-β vascular clearance in Alzheimer's diseaseLow-density lipoprotein receptor-related protein 1: a physiological Aβ homeostatic mechanism with multiple therapeutic opportunities.Neurovascular dysfunction and faulty amyloid β-peptide clearance in Alzheimer disease.The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease.Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies.Association between LRP1 C766T polymorphism and Alzheimer's disease susceptibility: a meta-analysis.Association of the C766T polymorphism of the low-density lipoprotein receptor-related protein gene with Alzheimer's disease.Lipoprotein lipase mutations and Alzheimer's disease.Elevation of LDL receptor-related protein levels via ligand interactions in Alzheimer disease and in vitro.The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons.The transcriptional factor LBP-1c/CP2/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease.Low density lipoprotein receptor-related protein gene polymorphisms and risk for late-onset Alzheimer's disease in a Japanese population.Common polymorphisms in LRP and A2M do not affect genetic risk for Alzheimer disease in Northern Ireland.Pigment Epithelium-Derived Factor Plays a Role in Alzheimer's Disease by Negatively Regulating Aβ42.
P2860
Q28588684-A64BF5A6-0854-4262-9965-B12B14631D47Q33588353-1238F0C0-F77B-4D03-B002-2ABF3C874F2AQ33827931-7F735CE8-87D5-4A47-A465-CF4C82964ACBQ33924453-F5D686CC-E69C-47A6-BB1B-2BBAD1697B0FQ34093057-D820E459-8CC5-4449-9566-9BFB65B5C357Q34274025-75A59CAB-B1D0-41AE-BC78-CBA70E26FAC4Q34368970-9EEB596D-90AD-467B-AA24-C339B6961060Q34960461-D114FB9F-C23C-4034-8D48-31688F47661EQ35023109-2D278B1E-EC67-46A9-9230-54D4E8F5972CQ35559895-0F544D91-D9F3-4196-9F04-DCCA817834B2Q36205039-BE4BE60D-5B2C-4B56-84BB-D14405BF599AQ36330297-E21FB374-4521-4ABE-B539-C8B8464CB5BDQ37232866-FA52EAFE-FD78-41AB-8906-5AE9530728ADQ39222720-D540343D-F524-4406-A5A4-70D156D11FF6Q41437365-101A71C5-E79B-444E-BEA8-8999DB6CF8D4Q44536830-4D0B92C0-1C4C-4F0F-8E43-0F945A38906CQ48235223-4F880339-7489-495D-A89C-D0299514AC1DQ48865152-EB211995-A922-4A87-AE38-45DC99DC647BQ53231417-ED43C83D-DF2B-4DC1-89D3-975F50942E78Q53343057-8B34D16B-36F5-4B4A-A948-31A09A560AEAQ53343783-0CE9CBBF-0560-411C-9A43-993B76A5DFD5Q53348037-8E2D103E-EF6A-4C6A-B2C1-59017B05CFA6Q53686278-0851FAA8-E6C5-4B2E-BAD1-BC48A38B1B96
P2860
Association at LRP gene locus with sporadic late-onset Alzheimer's disease.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Association at LRP gene locus with sporadic late-onset Alzheimer's disease.
@en
Association at LRP gene locus with sporadic late-onset Alzheimer's disease.
@nl
type
label
Association at LRP gene locus with sporadic late-onset Alzheimer's disease.
@en
Association at LRP gene locus with sporadic late-onset Alzheimer's disease.
@nl
prefLabel
Association at LRP gene locus with sporadic late-onset Alzheimer's disease.
@en
Association at LRP gene locus with sporadic late-onset Alzheimer's disease.
@nl
P50
P1433
P1476
Association at LRP gene locus with sporadic late-onset Alzheimer's disease
@en
P2093
F Wavrant-De Vrièze
P304
P356
10.1016/S0140-6736(05)78749-3
P407
P577
1998-06-01T00:00:00Z