Proteochemometric modeling of drug resistance over the mutational space for multiple HIV protease variants and multiple protease inhibitors.

Proteochemometric modeling of drug resistance over the mutational space for multiple HIV protease variants and multiple protease inhibitors.

Item
http://www.wikidata.org/entity/Q47948628
Structure-based methods for predicting target mutation-induced drug resistance and rational drug design to overcome the problemLinking the Resource Description Framework to cheminformatics and proteochemometricsWhich compound to select in lead optimization? Prospectively validated proteochemometric models guide preclinical developmentProteochemometric modeling of the bioactivity spectra of HIV-1 protease inhibitors by introducing protein-ligand interaction fingerprintSignificantly improved HIV inhibitor efficacy prediction employing proteochemometric models generated from antivirogram dataA unified proteochemometric model for prediction of inhibition of cytochrome p450 isoformsProteochemometric modeling of the antigen-antibody interaction: new fingerprints for antigen, antibody and epitope-paratope interactionMultivariate PLS Modeling of Apicomplexan FabD-Ligand Interaction Space for Mapping Target-Specific Chemical Space and Pharmacophore FingerprintsScreening of selective histone deacetylase inhibitors by proteochemometric modeling.Use of machine learning approaches for novel drug discovery.The recent progress in proteochemometric modelling: focusing on target descriptors, cross-term descriptors and application scope.Proteochemometric model for predicting the inhibition of penicillin-binding proteins.Benchmarking of protein descriptor sets in proteochemometric modeling (part 2): modeling performance of 13 amino acid descriptor sets.Biomacromolecular 3D-QSAR to Decipher Molecular Herbicide Resistance in Acetohydroxyacid Synthases.High-Dimensional descriptor selection and computational QSAR modeling for antitumor activity of ARC-111 analogues Based on Support Vector Regression (SVR).Proteochemometric Modeling of the Interaction Space of Carbonic Anhydrase and its Inhibitors: An Assessment of Structure-based and Sequence-based Descriptors.Proteochemometric modeling as a tool to design selective compounds and for extrapolating to novel targets
P2860

Proteochemometric modeling of drug resistance over the mutational space for multiple HIV protease variants and multiple protease inhibitors.

Item
http://www.wikidata.org/entity/Q47948628
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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name
Proteochemometric modeling of ...... multiple protease inhibitors.
@en
Proteochemometric modeling of ...... multiple protease inhibitors.
@nl
type
label
Proteochemometric modeling of ...... multiple protease inhibitors.
@en
Proteochemometric modeling of ...... multiple protease inhibitors.
@nl
prefLabel
Proteochemometric modeling of ...... multiple protease inhibitors.
@en
Proteochemometric modeling of ...... multiple protease inhibitors.
@nl
P1433
P1476
P304
P31
P356
P433
P478
P50
P577
P698
P921
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P1433
P1476
Proteochemometric modeling of ...... multiple protease inhibitors.
@en
P304
P31
P356
P433
P478
P50
P577
P698
P921