A cannabinoid type 2 receptor agonist attenuates blood-brain barrier damage and neurodegeneration in a murine model of traumatic brain injury.
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CB2 receptor activation prevents glial-derived neurotoxic mediator production, BBB leakage and peripheral immune cell infiltration and rescues dopamine neurons in the MPTP model of Parkinson's disease.The CB2 receptor and its role as a regulator of inflammationTargeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative DisordersPerformance of Male and Female C57BL/6J Mice on Motor and Cognitive Tasks Commonly Used in Pre-Clinical Traumatic Brain Injury ResearchA Novel Closed-Head Model of Mild Traumatic Brain Injury Using Focal Primary Overpressure Blast to the Cranium in Mice.Differential Expression of Brain Cannabinoid Receptors between Repeatedly Stressed Males and Females may Play a Role in Age and Gender-Related Difference in Traumatic Brain Injury: Implications from Animal Studies.Cannabinoid receptor type 2 agonist attenuates apoptosis by activation of phosphorylated CREB-Bcl-2 pathway after subarachnoid hemorrhage in rats.Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawalRegulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoyl-glycerol and arachidonoyl-ethanolamide, and their metabolites.Cannabinoid receptor type-2 stimulation, blockade, and deletion alter the vascular inflammatory responses to traumatic brain injury.Motor, visual and emotional deficits in mice after closed-head mild traumatic brain injury are alleviated by the novel CB2 inverse agonist SMM-189Changes in cannabinoid receptors, aquaporin 4 and vimentin expression after traumatic brain injury in adolescent male mice. Association with edema and neurological deficitCB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain.Trigeminal Pain Molecules, Allodynia, and Photosensitivity Are Pharmacologically and Genetically Modulated in a Model of Traumatic Brain Injury.Endocannabinoids in cerebrovascular regulation.Mild Traumatic Brain Injury Produces Neuron Loss That Can Be Rescued by Modulating Microglial Activation Using a CB2 Receptor Inverse Agonist.Endocannabinoids: A Promising Impact for Traumatic Brain Injury.Neuropsychiatric Symptom Modeling in Male and Female C57BL/6J Mice after Experimental Traumatic Brain Injury.Remote neurodegeneration: multiple actors for one play.Functions of the CB1 and CB 2 receptors in neuroprotection at the level of the blood-brain barrier.Cannabinoids in Neurodegenerative Disorders and Stroke/Brain Trauma: From Preclinical Models to Clinical Applications.Cannabinoid type 2 receptor stimulation attenuates brain edema by reducing cerebral leukocyte infiltration following subarachnoid hemorrhage in rats.Endocannabinoids modulate human blood-brain barrier permeability in vitroClinical studies and anti-inflammatory mechanisms of treatments.Delayed thalamic astrocytosis and disrupted sleep-wake patterns in a preclinical model of traumatic brain injury.β-Caryophyllene protects in vitro neurovascular unit against oxygen-glucose deprivation and re-oxygenation-induced injury.The Endocannabinoid System and Heart Disease: The Role of Cannabinoid Receptor Type 2.Male and female mice exhibit divergent responses of the cortical vasculature to traumatic brain injury.
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P2860
A cannabinoid type 2 receptor agonist attenuates blood-brain barrier damage and neurodegeneration in a murine model of traumatic brain injury.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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name
A cannabinoid type 2 receptor ...... del of traumatic brain injury.
@en
A cannabinoid type 2 receptor ...... del of traumatic brain injury.
@nl
type
label
A cannabinoid type 2 receptor ...... del of traumatic brain injury.
@en
A cannabinoid type 2 receptor ...... del of traumatic brain injury.
@nl
prefLabel
A cannabinoid type 2 receptor ...... del of traumatic brain injury.
@en
A cannabinoid type 2 receptor ...... del of traumatic brain injury.
@nl
P2093
P2860
P921
P356
P1476
A cannabinoid type 2 receptor ...... del of traumatic brain injury.
@en
P2093
Jack I Jallo
Melanie B Elliott
Peter S Amenta
Ronald F Tuma
P2860
P304
P356
10.1002/JNR.23114
P577
2012-08-18T00:00:00Z