about
A simple technique for quantifying apoptosis in 96-well platesOligomers of the Cdc7/Dbf4 protein kinase exist in the yeast cell.Alternative Treatments For Melanoma: Targeting BCL-2 Family Members to De-Bulk and Kill Cancer Stem CellsUltraviolet radiation induces release of MIA: a new mechanism for UVR-induced progression of melanomaMicroRNA-26a is strongly downregulated in melanoma and induces cell death through repression of silencer of death domains (SODD)The combination of BH3-mimetic ABT-737 with the alkylating agent temozolomide induces strong synergistic killing of melanoma cells independent of p53Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability.A simple protocol for using a LDH-based cytotoxicity assay to assess the effects of death and growth inhibition at the same time.CtBP1 is expressed in melanoma and represses the transcription of p16INK4a and Brca1.IMPACT: a whole-exome sequencing analysis pipeline for integrating molecular profiles with actionable therapeutics in clinical samples.Combining a GSI and BCL-2 inhibitor to overcome melanoma's resistance to current treatments.miR in melanoma development: miRNAs and acquired hallmarks of cancer in melanoma.Combining a BCL2 inhibitor with the retinoid derivative fenretinide targets melanoma cells including melanoma initiating cellsBH3 mimetic ABT-737 and a proteasome inhibitor synergistically kill melanomas through Noxa-dependent apoptosis.Active N-Ras and B-Raf inhibit anoikis by downregulating Bim expression in melanocytic cells.Hyperthermia induces endoplasmic reticulum-mediated apoptosis in melanoma and non-melanoma skin cancer cells.Generation of a prophylactic melanoma vaccine using whole recombinant yeast expressing MART-1.Induction of secreted matrix metalloproteinase-9 activity in human melanoma cells by extracellular matrix proteins and cytokines.RhoC promotes human melanoma invasion in a PI3K/Akt-dependent pathway.Lovastatin-induced apoptosis in human melanoma cell lines.Fast response temperature measurement and highly reproducible heating methods for 96-well plates.Maternal anti-HBVs suppress the immune response of infants to hepatitis B vaccine.Release of vascular endothelial growth factor from a human melanoma cell line, WM35, is induced by hypoxia but not ultraviolet radiation and is potentiated by activated Ras mutation.Regulation of Fas-mediated apoptosis by N-ras in melanoma.Expression of activated N-ras in a primary melanoma cell line counteracts growth inhibition by transforming growth factor-beta.NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma.Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells.Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma.ALK Inhibitor Response in Melanomas Expressing EML4-ALK Fusions and Alternate ALK Isoforms.Repigmentation of Human Vitiligo Skin by NBUVB Is Controlled by Transcription of GLI1 and Activation of the β-Catenin Pathway in the Hair Follicle Bulge Stem Cells.Biphasic pro-melanogenic and pro-apoptotic effects of all-trans-retinoic acid (ATRA) on human melanocytes: time-course study.Ultraviolet radiation induces release of MIA: A new mechanism for UVR-induced progression of melanomaBH3 mimetics induce apoptosis independent of DRP-1 in melanomaIdentification and characterization of individual cyclin-dependent kinase complexes from Saccharomyces cerevisiaeMCL1 inhibitors S63845/MIK665 plus Navitoclax synergistically kill difficult-to-treat melanoma cells
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P50
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wetenschapper
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հետազոտող
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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Yiqun Shellman
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P106
P31
P496
0000-0003-0598-5753