Evidence that cytochrome b5 and cytochrome b5 reductase can act as sole electron donors to the hepatic cytochrome P450 system.
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The Role of Protein-Protein and Protein-Membrane Interactions on P450 FunctionCytochrome b5 reductase and the control of lipid metabolism and healthspan.Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicityThe anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN™) mice and pure enzymes.Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implicationsAnalysis of cytochrome b(5) reductase-mediated metabolism in the phytopathogenic fungus Zymoseptoria tritici reveals novel functionalities implicated in virulence.A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches.NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene.Zinc finger nuclease knock-out of NADPH:cytochrome P450 oxidoreductase (POR) in human tumor cell lines demonstrates that hypoxia-activated prodrugs differ in POR dependence.The functional effects of physical interactions involving cytochromes P450: putative mechanisms of action and the extent of these effects in biological membranes.NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1.The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers.Advances in the Understanding of Protein-Protein Interactions in Drug Metabolizing Enzymes through the Use of Biophysical Techniques.Cytochrome b5 plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine.Cytochrome b5 Reductase 3 Modulates Soluble Guanylate Cyclase Redox State and cGMP Signaling.siRNA-mediated knockdown of P450 oxidoreductase in rats: a tool to reduce metabolism by CYPs and increase exposure of high clearance compounds.Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice.Membrane topology and search for potential redox partners of colon cancer-specific cytochrome P450 2W1.
P2860
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P2860
Evidence that cytochrome b5 and cytochrome b5 reductase can act as sole electron donors to the hepatic cytochrome P450 system.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
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2013年學術文章
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name
Evidence that cytochrome b5 an ...... epatic cytochrome P450 system.
@en
Evidence that cytochrome b5 an ...... epatic cytochrome P450 system.
@nl
type
label
Evidence that cytochrome b5 an ...... epatic cytochrome P450 system.
@en
Evidence that cytochrome b5 an ...... epatic cytochrome P450 system.
@nl
prefLabel
Evidence that cytochrome b5 an ...... epatic cytochrome P450 system.
@en
Evidence that cytochrome b5 an ...... epatic cytochrome P450 system.
@nl
P356
P1476
Evidence that cytochrome b5 an ...... epatic cytochrome P450 system.
@en
P2093
C Roland Wolf
Lesley A McLaughlin
P304
P356
10.1124/MOL.112.084616
P577
2013-03-25T00:00:00Z