Mechanisms by which transcription can regulate somatic hypermutation.
about
Advances in mechanisms of genetic instability related to hereditary neurological diseases.Ectopic expression of AID in a non-B cell line triggers A:T and G:C point mutations in non-replicating episomal vectors.Non-B DNA conformations, genomic rearrangements, and human disease.On the molecular mechanism of somatic hypermutation of rearranged immunoglobulin genes.Evaluation of molecular models for the affinity maturation of antibodies: roles of cytosine deamination by AID and DNA repairPost-translational regulation of activation-induced cytidine deaminase.G4-forming sequences in the non-transcribed DNA strand pose blocks to T7 RNA polymerase and mammalian RNA polymerase II.Transcriptional de-repression and Mfd are mutagenic in stressed Bacillus subtilis cells.II. Correlations between secondary structure stability and mutation frequency during somatic hypermutation.Gene Conversion-Like Events in the Diversification of Human Rearranged IGHV3-23*01 Gene Sequences.I. VH gene transcription creates stabilized secondary structures for coordinated mutagenesis during somatic hypermutation.Stabilised DNA secondary structures with increasing transcription localise hypermutable bases for somatic hypermutation in IGHV3-23.Hypothesis: biological role for J-C intronic matrix attachment regions in the molecular mechanism of antigen-driven somatic hypermutation.
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P2860
Mechanisms by which transcription can regulate somatic hypermutation.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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name
Mechanisms by which transcription can regulate somatic hypermutation.
@en
Mechanisms by which transcription can regulate somatic hypermutation.
@nl
type
label
Mechanisms by which transcription can regulate somatic hypermutation.
@en
Mechanisms by which transcription can regulate somatic hypermutation.
@nl
prefLabel
Mechanisms by which transcription can regulate somatic hypermutation.
@en
Mechanisms by which transcription can regulate somatic hypermutation.
@nl
P2093
P2860
P356
P1433
P1476
Mechanisms by which transcription can regulate somatic hypermutation.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.GENE.6364053
P577
2004-05-01T00:00:00Z