The lid subdomain of DnaK is required for the stabilization of the substrate-binding site.
about
Plasmodium falciparum Hsp70-x: a heat shock protein at the host-parasite interfaceHSPA8/HSC70 chaperone protein: structure, function, and chemical targeting.Pathways of allosteric regulation in Hsp70 chaperones.Ionic contacts at DnaK substrate binding domain involved in the allosteric regulation of lid dynamics.J domain co-chaperone specificity defines the role of BiP during protein translocationHsp70 oligomerization is mediated by an interaction between the interdomain linker and the substrate-binding domain.Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and CommunicationComplementation of an Escherichia coli DnaK defect by Hsc70-DnaK chimeric proteins.Novel Entropically Driven Conformation-specific Interactions with Tomm34 Protein Modulate Hsp70 Protein Folding and ATPase Activities.Unique peptide substrate binding properties of 110-kDa heat-shock protein (Hsp110) determine its distinct chaperone activityTracking the interplay between bound peptide and the lid domain of DnaK, using molecular dynamics.An interdomain energetic tug-of-war creates the allosterically active state in Hsp70 molecular chaperones.The allosteric transition in DnaK probed by infrared difference spectroscopy. Concerted ATP-induced rearrangement of the substrate binding domain.Direct comparison of a stable isolated Hsp70 substrate-binding domain in the empty and substrate-bound states.DnaJ recruits DnaK to protein aggregates.Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions.In silico mutational studies of Hsp70 disclose sites with distinct functional attributes.Hsp70 chaperone: a master player in protein homeostasis
P2860
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P2860
The lid subdomain of DnaK is required for the stabilization of the substrate-binding site.
description
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name
The lid subdomain of DnaK is r ...... of the substrate-binding site.
@en
The lid subdomain of DnaK is r ...... of the substrate-binding site.
@nl
type
label
The lid subdomain of DnaK is r ...... of the substrate-binding site.
@en
The lid subdomain of DnaK is r ...... of the substrate-binding site.
@nl
prefLabel
The lid subdomain of DnaK is r ...... of the substrate-binding site.
@en
The lid subdomain of DnaK is r ...... of the substrate-binding site.
@nl
P2860
P356
P1476
The lid subdomain of DnaK is r ...... of the substrate-binding site.
@en
P2093
Fernando Moro
Vanesa Fernández-Sáiz
P2860
P304
19600-19606
P356
10.1074/JBC.M400921200
P407
P50
P577
2004-02-25T00:00:00Z