Comparison of the human and murine ATRX gene identifies highly conserved, functionally important domains.
about
The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodiesThe chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesisComparative analysis of the ATRX promoter and 5' regulatory region reveals conserved regulatory elements which are linked to roles in neurodevelopment, alpha-globin regulation and testicular functionUniversal fast walking applied to cDNA.Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues.ATRX has a critical and conserved role in mammalian sexual differentiationAnalysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin loopingMolecular-clinical spectrum of the ATR-X syndrome.Sex determining genes and sexual differentiation in a marsupial.Loss of Atrx sensitizes cells to DNA damaging agents through p53-mediated death pathwaysATR-X mutations cause impaired nuclear location and altered DNA binding properties of the XNP/ATR-X proteinRole of ATRX in chromatin structure and function: implications for chromosome instability and human diseaseDefining the cause of skewed X-chromosome inactivation in X-linked mental retardation by use of a mouse modelα-Thalassemia, mental retardation, and myelodysplastic syndrome.Compromised genomic integrity impedes muscle growth after Atrx inactivation.The human sex-reversing ATRX gene has a homologue on the marsupial Y chromosome, ATRY: implications for the evolution of mammalian sex determination.Emerging roles of ATRX in cancer.Syndromic disorder of sex development due to a novel hemizygous mutation in the carboxyl-terminal domain of ATRX.Structure and Mechanisms of SF1 DNA Helicases.Developmental competence in oocytes and cumulus cells: candidate genes and networks.Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice.ATRX in chromatin assembly and genome architecture during development and disease.
P2860
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P2860
Comparison of the human and murine ATRX gene identifies highly conserved, functionally important domains.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Comparison of the human and mu ...... unctionally important domains.
@en
Comparison of the human and mu ...... unctionally important domains.
@nl
type
label
Comparison of the human and mu ...... unctionally important domains.
@en
Comparison of the human and mu ...... unctionally important domains.
@nl
prefLabel
Comparison of the human and mu ...... unctionally important domains.
@en
Comparison of the human and mu ...... unctionally important domains.
@nl
P2093
P2860
P356
P1433
P1476
Comparison of the human and mu ...... unctionally important domains.
@en
P2093
A O Tastan
D J Picketts
P2860
P2888
P304
P356
10.1007/S003359900781
P577
1998-05-01T00:00:00Z