Optimizing the cell efficacy of synthetic ribozymes. Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb.

Optimizing the cell efficacy of synthetic ribozymes. Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb.

Item
http://www.wikidata.org/entity/Q48057859
Secondary structure prediction and in vitro accessibility of mRNA as tools in the selection of target sites for ribozymesCombinatorial screening and intracellular antiviral activity of hairpin ribozymes directed against hepatitis B virus.Construction of a directed hammerhead ribozyme library: towards the identification of optimal target sites for antisense-mediated gene inhibition.Cleavage of highly structured viral RNA molecules by combinatorial libraries of hairpin ribozymes. The most effective ribozymes are not predicted by substrate selection rules.Selection, design, and characterization of a new potentially therapeutic ribozyme.Current status of ribozymes as gene therapy agents for cancer.Synthetic hammerhead ribozymes as tools in gene expression.The effect of structure in a long target RNA on ribozyme cleavage efficiency.Development of lead hammerhead ribozyme candidates against human rod opsin mRNA for retinal degeneration therapy.tRNAVal-heterodimeric maxizymes with high potential as geneinactivating agents: simultaneous cleavage at two sites in HIV-1 Tat mRNA in cultured cells.Comparative study of DNA enzymes and ribozymes against the same full-length messenger RNA of the vanilloid receptor subtype I.Identifying ribozyme-accessible sites using NUH triplet-targeting gapmers.Extending the cleavage rules for the hammerhead ribozyme: mutating adenosine15.1 to inosine15.1 changes the cleavage site specificity from N16.2U16.1H17 to N16.2C16.1H17.Recent developments in the hammerhead ribozyme field.Inhibition of luciferase expression by synthetic hammerhead ribozymes and their cellular uptakeEfficient transfer of synthetic ribozymes into cells using hemagglutinating virus of Japan (HVJ)-cationic liposomes. Application for ribozymes that target human t-cell leukemia virus type I tax/rex mRNA.Clearing the way for ribozymes.
P2860

Optimizing the cell efficacy of synthetic ribozymes. Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb.

Item
http://www.wikidata.org/entity/Q48057859
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
Optimizing the cell efficacy o ...... ting the proto-oncogene c-myb.
@en
Optimizing the cell efficacy o ...... ting the proto-oncogene c-myb.
@nl
type
label
Optimizing the cell efficacy o ...... ting the proto-oncogene c-myb.
@en
Optimizing the cell efficacy o ...... ting the proto-oncogene c-myb.
@nl
prefLabel
Optimizing the cell efficacy o ...... ting the proto-oncogene c-myb.
@en
Optimizing the cell efficacy o ...... ting the proto-oncogene c-myb.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Optimizing the cell efficacy o ...... ting the proto-oncogene c-myb.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698